Nuno Dinis Alves
Overview
Explore the profile of Nuno Dinis Alves including associated specialties, affiliations and a list of published articles.
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10
Citations
48
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Recent Articles
1.
Martins-Macedo J, Araujo B, Anjo S, Silveira-Rosa T, Patricio P, Alves N, et al.
Mol Psychiatry
. 2024 Mar;
29(7):2185-2198.
PMID: 38454085
Adult cytogenesis, the continuous generation of newly-born neurons (neurogenesis) and glial cells (gliogenesis) throughout life, is highly impaired in several neuropsychiatric disorders, such as Major Depressive Disorder (MDD), impacting negatively...
2.
3.
Machado-Santos A, Loureiro-Campos E, Patricio P, Araujo B, Alves N, Mateus-Pinheiro A, et al.
Cells
. 2022 Feb;
11(3).
PMID: 35159199
Depression is a prevalent, socially burdensome disease. Different studies have demonstrated the important role of astrocytes in the pathophysiology of depression as modulators of neurotransmission and neurovascular coupling. This is...
4.
Silveira-Rosa T, Mateus-Pinheiro A, Correia J, Silva J, Martins-Macedo J, Araujo B, et al.
Cell Prolif
. 2021 Dec;
55(2):e13165.
PMID: 34970787
Objectives: The action of stress hormones, mainly glucocorticoids, starts and coordinates the systemic response to stressful events. The HPA axis activity is predicated on information processing and modulation by upstream...
5.
Loureiro-Campos E, Mateus-Pinheiro A, Patricio P, Soares-Cunha C, Silva J, Sardinha V, et al.
Elife
. 2021 Dec;
10.
PMID: 34859784
The transcription factor activating protein two gamma (AP2γ) is an important regulator of neurogenesis both during embryonic development as well as in the postnatal brain, but its role for neurophysiology...
6.
Patricio P, Mateus-Pinheiro A, Machado-Santos A, Alves N, Correia J, Morais M, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769232
Changes in adult hippocampal cell proliferation and genesis have been largely implicated in depression and antidepressant action, though surprisingly, the underlying cell cycle mechanisms are largely undisclosed. Using both an...
7.
Mateus-Pinheiro A, Patricio P, Alves N, Martins-Macedo J, Caetano I, Silveira-Rosa T, et al.
Mol Psychiatry
. 2021 Sep;
26(12):7154-7166.
PMID: 34521994
Impaired ability to generate new cells in the adult brain has been linked to deficits in multiple emotional and cognitive behavioral domains. However, the mechanisms by which abrogation of adult...
8.
Patricio P, Mateus-Pinheiro A, Alves N, Morais M, Rodrigues A, Bessa J, et al.
Front Behav Neurosci
. 2020 Aug;
14:136.
PMID: 32848656
Depression is a chronic debilitating disorder predicted to affect around 20% of the world population. Both brain and peripheral changes, including neuroplastic changes have been shown to occur in the...
9.
Duarte J, Gaspar R, Caetano L, Patricio P, Soares-Cunha C, Mateus-Pinheiro A, et al.
Glia
. 2018 Nov;
67(1):182-192.
PMID: 30461068
Epidemiologic studies have provided compelling evidence that prenatal stress, through excessive maternal glucocorticoids exposure, is associated with psychiatric disorders later in life. We have recently reported that anxiety associated with...
10.
Mateus-Pinheiro A, Alves N, Sousa N, Pinto L
J Exp Neurosci
. 2018 Apr;
12:1179069518766897.
PMID: 29636632
Since the recognition that the mammalian brain retains the ability to generate newborn neurons with functional relevance throughout life, the matrix of molecular regulators that govern adult neurogenesis has been...