Author: Numa Dancause

1.

Local Field Potential Biomarkers of Non-Motor Symptoms in Parkinson's Disease: Insights From the Subthalamic Nucleus in Deep Brain Stimulation

Gobeil M, Guillemette A, Silhadi M, Charbonneau L, Bergeron D, Dominguez-Vargas A, et al.

Eur J Neurosci . 2025 Mar; 61(5):e70046. PMID: 40040306

Non-motor symptoms can severely affect the quality of life of Parkinson's disease-afflicted patients, with the most common ones being pain, sleep impairments, and neuropsychiatric manifestations. In advanced cases, complex fluctuations...

2.

Post-Stroke Recovery in Relation to Parvalbumin-Positive Interneurons and Perineuronal Nets

Kuhl L, Jeffers M, Hristozov N, Karthikeyan S, McDonald M, Hufnagel A, et al.

Neurorehabil Neural Repair . 2025 Jan; 15459683241309567. PMID: 39819253

Background: There is a critical time window of post-stroke neuroplasticity when spontaneous behavioral recovery occurs. Potential factors responsible for this heightened plasticity are the reduction of parvalbumin-immunoreactive (PV+) interneuron inhibitory...

3.

3D ultrasound localization microscopy of the nonhuman primate brain

Xing P, Perrot V, Dominguez-Vargas A, Poree J, Quessy S, Dancause N, et al.

EBioMedicine . 2024 Dec; 111():105457. PMID: 39708427

Background: Haemodynamic changes occur in stroke and neurodegenerative diseases. Developing imaging techniques allowing the in vivo visualisation and quantification of cerebral blood flow would help better understand the underlying mechanism...

4.

Variations in Clustering of Multielectrode Local Field Potentials in the Motor Cortex of Macaque Monkeys during a Reach-and-Grasp Task

Chambellant F, Falaki A, Moreau-Debord I, French R, Serrano E, Quessy S, et al.

eNeuro . 2024 Sep; 11(9). PMID: 39288997

There is experimental evidence of varying correlation among the elements of the neuromuscular system over the course of the reach-and-grasp task. The aim of this study was to investigate if...

5.

Porcine Model of Cerebral Ischemic Stroke Utilizing Intracortical Recordings for the Continuous Monitoring of the Ischemic Area

Norgaard Dos Santos Nielsen T, Dancause N, Janjua T, Andreis F, Kjaergaard B, Jensen W

Sensors (Basel) . 2024 May; 24(10). PMID: 38793822

Purpose: Our aim was to use intracortical recording to enable the tracking of ischemic infarct development over the first few critical hours of ischemia with a high time resolution in...

6.

Differential Modulation of Local Field Potentials in the Primary and Premotor Cortices during Ipsilateral and Contralateral Reach to Grasp in Macaque Monkeys

Falaki A, Quessy S, Dancause N

J Neurosci . 2024 Apr; 44(21). PMID: 38589229

Hand movements are associated with modulations of neuronal activity across several interconnected cortical areas, including the primary motor cortex (M1) and the dorsal and ventral premotor cortices (PMd and PMv)....

7.

Gaussian-process-based Bayesian optimization for neurostimulation interventions in rats

Choiniere L, Guay-Hottin R, Picard R, Lajoie G, Bonizzato M, Dancause N

STAR Protoc . 2024 Feb; 5(1):102885. PMID: 38358881

Effective neural stimulation requires adequate parametrization. Gaussian-process (GP)-based Bayesian optimization (BO) offers a framework to discover optimal stimulation parameters in real time. Here, we first provide a general protocol to...

8.

A translational roadmap for transcranial magnetic and direct current stimulation in stroke rehabilitation: Consensus-based core recommendations from the third stroke recovery and rehabilitation roundtable

Edwards J, Dominguez-Vargas A, Rosso C, Branscheidt M, Sheehy L, Quandt F, et al.

Neurorehabil Neural Repair . 2023 Oct; 38(1):19-29. PMID: 37837350

Background And Aims: The purpose of this Third Stroke Recovery and Rehabilitation Roundtable (SRRR3) was to develop consensus recommendations to address outstanding barriers for the translation of preclinical and clinical...

9.

A translational roadmap for transcranial magnetic and direct current stimulation in stroke rehabilitation: Consensus-based core recommendations from the third stroke recovery and rehabilitation roundtable

Edwards J, Dominguez-Vargas A, Rosso C, Branscheidt M, Sheehy L, Quandt F, et al.

Int J Stroke . 2023 Oct; 19(2):145-157. PMID: 37824726

Background And Aims: The purpose of this Third Stroke Recovery and Rehabilitation Roundtable (SRRR3) was to develop consensus recommendations to address outstanding barriers for the translation of preclinical and clinical...

10.

Enriched Rehabilitation Reduces Abnormal Motor Synergies and Enhances Motor Plasticity Following Severe Stroke in Rats

Balbinot G, Touvykine B, Zaftis J, Pedrini Schuch C, Jeffers M, Elgbeili G, et al.

Stroke . 2023 Jul; 54(8):2156-2166. PMID: 37439205

Background: Stroke results in loss of upper motor neuron control over voluntary movements and emergence of abnormal synergies. Presently, it is unclear to what extent poststroke recovery reflects true recovery...