Norman E Taylor
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Explore the profile of Norman E Taylor including associated specialties, affiliations and a list of published articles.
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22
Citations
872
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Recent Articles
11.
Zhang H, Zhao H, Zeng C, Van Dort C, Faingold C, Taylor N, et al.
Neurobiol Dis
. 2017 Nov;
110:47-58.
PMID: 29141182
Sudden unexpected death in epilepsy (SUDEP) is a devastating epilepsy complication. Seizure-induced respiratory arrest (S-IRA) occurs in many witnessed SUDEP patients and animal models as an initiating event leading to...
12.
Guidera J, Taylor N, Lee J, Vlasov K, Pei J, Stephen E, et al.
Front Neural Circuits
. 2017 Jul;
11:36.
PMID: 28725184
Although general anesthetics are routinely administered to surgical patients to induce loss of consciousness, the mechanisms underlying anesthetic-induced unconsciousness are not fully understood. In rats, we characterized changes in the...
13.
Taylor N, Van Dort C, Kenny J, Pei J, Guidera J, Vlasov K, et al.
Proc Natl Acad Sci U S A
. 2016 Oct;
113(45):12826-12831.
PMID: 27791160
Dopamine (DA) promotes wakefulness, and DA transporter inhibitors such as dextroamphetamine and methylphenidate are effective for increasing arousal and inducing reanimation, or active emergence from general anesthesia. DA neurons in...
14.
Kenny J, Chemali J, Cotten J, Van Dort C, Kim S, Ba D, et al.
Anesth Analg
. 2016 Mar;
123(5):1210-1219.
PMID: 26991753
Background: Although emergence from general anesthesia is clinically treated as a passive process driven by the pharmacokinetics of drug clearance, agents that hasten recovery from general anesthesia may be useful...
15.
Muindi F, Kenny J, Taylor N, Solt K, Wilson M, Brown E, et al.
Behav Brain Res
. 2016 Mar;
306:20-5.
PMID: 26971629
Clinically, emergence from general anesthesia is viewed as a passive process where anesthetics are discontinued at the end of surgery and anesthesiologists wait for the drugs to wear off. The...
16.
Kenny J, Taylor N, Brown E, Solt K
PLoS One
. 2015 Jul;
10(7):e0131914.
PMID: 26148114
Methylphenidate induces reanimation (active emergence) from general anesthesia in rodents, and recent evidence suggests that dopaminergic neurotransmission is important in producing this effect. Dextroamphetamine causes the direct release of dopamine...
17.
Solt K, Van Dort C, Chemali J, Taylor N, Kenny J, Brown E
Anesthesiology
. 2014 Jan;
121(2):311-9.
PMID: 24398816
Background: Methylphenidate or a D1 dopamine receptor agonist induces reanimation (active emergence) from general anesthesia. The authors tested whether electrical stimulation of dopaminergic nuclei also induces reanimation from general anesthesia....
18.
Taylor N, Chemali J, Brown E, Solt K
Anesthesiology
. 2012 Dec;
118(1):30-9.
PMID: 23221866
Background: A recent study showed that methylphenidate induces emergence from isoflurane anesthesia. Methylphenidate inhibits dopamine and norepinephrine reuptake transporters. The objective of this study was to test the hypothesis that...
19.
Liu Y, Taylor N, Lu L, Usa K, Cowley Jr A, Ferreri N, et al.
Hypertension
. 2010 Mar;
55(4):974-82.
PMID: 20194304
MicroRNAs are endogenous repressors of gene expression. We examined microRNAs in the renal medulla of Dahl salt-sensitive rats and consomic SS-13(BN) rats. Salt-induced hypertension and renal injury in Dahl salt-sensitive...
20.
Taylor N, Maier K, Roman R, Cowley Jr A
Hypertension
. 2006 Oct;
48(6):1066-71.
PMID: 17060509
NO synthase (NOS) can paradoxically contribute to the production of reactive oxygen species when l-arginine or the cofactor R-tetrahydrobiopterin (BH(4)) becomes limited. The present study examined whether NOS contributes to...