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Norma Hernandez-Pedro

Explore the profile of Norma Hernandez-Pedro including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 419
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Recent Articles
1.
Ramos-Ramirez M, Caballe-Perez E, Lucio-Lozada J, Romero-Nunez E, Castillo-Ruiz C, Dorantes-Sanchez L, et al.
Cancer Metastasis Rev . 2025 Feb; 44(1):30. PMID: 39915358
Immune checkpoint inhibitors (ICIs) have improved clinical outcomes in patients with non-small cell lung cancer (NSCLC) lacking targetable oncogenic alterations. However, their efficacy in individuals with such genomic alterations remains...
2.
Hernandez-Martinez J, Guijosa A, Flores-Estrada D, Cruz-Rico G, Turcott J, Hernandez-Pedro N, et al.
JCO Glob Oncol . 2024 Dec; 10:e2400338. PMID: 39637345
Purpose: Targeted therapies are indicated for patients with non-small cell lung cancer (NSCLC) and driver tumor mutations. However, real-world studies on the survival benefits of these agents are limited. This...
3.
Arrieta O, Caballe-Perez E, Hernandez-Pedro N, Romero-Nunez E, Lucio-Lozada J, Castillo-Ruiz C, et al.
Lung Cancer . 2024 Jun; 194:107864. PMID: 38945003
Introduction: Pathogenic or likely pathogenic germline variants (PGVs) in cancer predisposition genes may play a role in lung cancer (LC) susceptibility. However, determining an eligible population for genetic testing remains...
4.
Aviles-Salas A, Cabrera-Miranda L, Hernandez-Pedro N, Vargas-Lias D, Samtani S, Munoz-Montano W, et al.
Front Oncol . 2023 Dec; 13:1269029. PMID: 38111532
Background: Programmed death ligand-1 (PD-L1) expression is a predictive biomarker in patients with lung cancer, but its role in malignant pleural mesothelioma (MPM) remains unclear. Evidence suggests that higher PD-L1...
5.
Hernandez-Pedro N, Arroyo-Hernandez M, Barrios-Bernal P, Romero-Nunez E, Sosa-Hernandez V, Avila-Rios S, et al.
Vaccines (Basel) . 2023 Oct; 11(10). PMID: 37897014
Immune dysregulation and cancer treatment may affect SARS-CoV-2 vaccination protection. Antibody production by B-cells play a vital role in the control and clearance of the SARS-CoV-2 virus. This study prospectively...
6.
Caballe-Perez E, Hernandez-Pedro N, Ramos-Ramirez M, Barrios-Bernal P, Romero-Nunez E, Lucio-Lozada J, et al.
Clin Transl Oncol . 2023 Jul; 26(4):836-850. PMID: 37490263
Purpose: Mutations in the Kirsten rat sarcoma viral (KRAS) oncogene constitute a significant driver of lung adenocarcinoma, present in 10-40% of patients, which exhibit heterogeneous clinical outcomes, mainly driven by...
7.
Barrios-Bernal P, Hernandez-Pedro N, Lara-Mejia L, Arrieta O
Oncotarget . 2023 Jul; 14:670-671. PMID: 37395790
No abstract available.
8.
Barrios-Bernal P, Lucio-Lozada J, Ramos-Ramirez M, Hernandez-Pedro N, Arrieta O
Int J Mol Sci . 2023 Mar; 24(5). PMID: 36901764
Novel inhibitors of KRAS with G12C mutation (sotorasib) have demonstrated short-lasting responses due to resistance mediated by the AKT-mTOR-P70S6K pathway. In this context, metformin is a promising candidate to break...
9.
Barrios-Bernal P, Zatarain-Barron Z, Hernandez-Pedro N, Orozco-Morales M, Olivera-Ramirez A, Avila-Moreno F, et al.
Pharmaceuticals (Basel) . 2022 Jul; 15(7). PMID: 35890085
Metformin has been under basic and clinical study as an oncological repurposing pharmacological agent for several years, stemming from observational studies which consistently evidenced that subjects who were treated with...
10.
Barrios-Bernal P, Hernandez-Pedro N, Orozco-Morales M, Viedma-Rodriguez R, Lucio-Lozada J, Avila-Moreno F, et al.
Pharmaceuticals (Basel) . 2022 Mar; 15(3). PMID: 35337178
The combination of metformin and TKIs for non-small cell lung cancer has been proposed as a strategy to overcome resistance of neoplastic cells induced by several molecular mechanisms. This study...