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Noel Malod-Dognin

Explore the profile of Noel Malod-Dognin including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 1090
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Recent Articles
1.
Przulj N, Malod-Dognin N
Bioinform Adv . 2025 Feb; 5(1):vbae164. PMID: 39927291
Motivation: Heterogeneous, interconnected, systems-level, molecular (multi-omic) data have become increasingly available and key in precision medicine. We need to utilize them to better stratify patients into risk groups, discover new...
2.
Windels S, Tello Velasco D, Rotkevich M, Malod-Dognin N, Przulj N
Bioinformatics . 2024 Nov; 40(11). PMID: 39495120
Motivation: Spatial Analysis of Functional Enrichment (SAFE) is a popular tool for biologists to investigate the functional organization of biological networks via highly intuitive 2D functional maps. To create these...
3.
Doria-Belenguer S, Xenos A, Ceddia G, Malod-Dognin N, Przulj N
Bioinform Adv . 2024 Jun; 4(1):vbae075. PMID: 38827411
Summary: Common approaches for deciphering biological networks involve network embedding algorithms. These approaches strictly focus on clustering the genes' embedding vectors and interpreting such clusters to reveal the hidden information...
4.
Maier A, Hartung M, Abovsky M, Adamowicz K, Bader G, Baier S, et al.
Nucleic Acids Res . 2024 May; 52(W1):W481-W488. PMID: 38783119
In recent decades, the development of new drugs has become increasingly expensive and inefficient, and the molecular mechanisms of most pharmaceuticals remain poorly understood. In response, computational systems and network...
5.
Mihajlovic K, Ceddia G, Malod-Dognin N, Novak G, Kyriakis D, Skupin A, et al.
Sci Rep . 2024 May; 14(1):10983. PMID: 38744869
Parkinson's disease (PD) is a complex neurodegenerative disorder without a cure. The onset of PD symptoms corresponds to 50% loss of midbrain dopaminergic (mDA) neurons, limiting early-stage understanding of PD....
6.
Gureghian V, Herbst H, Kozar I, Mihajlovic K, Malod-Dognin N, Ceddia G, et al.
Cancer Gene Ther . 2023 Jul; 30(10):1330-1345. PMID: 37420093
Therapy Induced Senescence (TIS) leads to sustained growth arrest of cancer cells. The associated cytostasis has been shown to be reversible and cells escaping senescence further enhance the aggressiveness of...
7.
Maier A, Hartung M, Abovsky M, Adamowicz K, Bader G, Baier S, et al.
ArXiv . 2023 Jun; PMID: 37332567
In recent decades, the development of new drugs has become increasingly expensive and inefficient, and the molecular mechanisms of most pharmaceuticals remain poorly understood. In response, computational systems and network...
8.
Malod-Dognin N, Ceddia G, Gvozdenov M, Tomic B, Dunjic Manevski S, Djordjevic V, et al.
PLoS One . 2023 Apr; 18(4):e0284084. PMID: 37098010
Antithrombin resistance is a rare subtype of hereditary thrombophilia caused by prothrombin gene variants, leading to thrombotic disorders. Recently, the Prothrombin Belgrade variant has been reported as a specific variant...
9.
Doria-Belenguer S, Xenos A, Ceddia G, Malod-Dognin N, Przulj N
Bioinformatics . 2023 Apr; 39(5). PMID: 37084262
Motivation: Advances in omics technologies have revolutionized cancer research by producing massive datasets. Common approaches to deciphering these complex data are by embedding algorithms of molecular interaction networks. These algorithms...
10.
Xenos A, Malod-Dognin N, Zambrana C, Przulj N
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36674947
The COVID-19 pandemic is an acute and rapidly evolving global health crisis. To better understand this disease's molecular basis and design therapeutic strategies, we built upon the recently proposed concept...