Nobuyuki Hirai
Overview
Explore the profile of Nobuyuki Hirai including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
117
Followers
0
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Recent Articles
1.
Ichinose M, Endo K, Hirai N, Kobayashi E, Ueno T, Nakanishi Y, et al.
Nutr Cancer
. 2025 Feb;
:1-11.
PMID: 39966705
Sarcopenia is common in patients with head and neck cancer and is suggested to be associated with decreased survival. This study aimed to investigate the relationship between changes in skeletal...
2.
Endo K, Ichinose M, Kobayashi E, Ueno T, Hirai N, Nakanishi Y, et al.
Cancers (Basel)
. 2024 Oct;
16(20).
PMID: 39456555
Sarcopenia is recognized as a crucial factor impacting the prognosis, treatment responses, and quality of life of HNC patients. This review discusses various mechanisms, including common etiological factors, such as...
3.
Uno D, Endo K, Yoshikawa T, Hirai N, Kobayashi E, Nakanishi Y, et al.
Thyroid Res
. 2024 Sep;
17(1):21.
PMID: 39278941
Introduction: Activation of the MAPK pathway by genetic mutations (such as BRAF and RET) initiates and accelerates the growth of papillary thyroid carcinoma (PTC). However, the correlation between genetic mutations...
4.
Kitagawa Y, Kondo S, Fukuyo M, Wakae K, Dochi H, Mizokami H, et al.
Cancer Sci
. 2024 Aug;
115(11):3587-3595.
PMID: 39196700
Cancer cells show a dynamic metabolic landscape, requiring a sufficient supply of nucleotides to proliferate. They are highly dependent on de novo purine biosynthetic pathways for their nucleotide requirements. Phosphoribosyl...
5.
Dochi H, Kondo S, Komura S, Moriyama-Kita M, Komori T, Nanbo A, et al.
Int J Cancer
. 2023 Nov;
154(5):895-911.
PMID: 37907830
Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) cells have high metastatic potential. Recent research has revealed that the interaction of between tumor cells and the surrounding stroma plays an important role...
6.
Kobayashi E, Kondo S, Dochi H, Moriyama-Kita M, Hirai N, Komori T, et al.
Cancers (Basel)
. 2022 Jun;
14(12).
PMID: 35740492
Nasopharyngeal carcinoma (NPC) is one of the Epstein-Barr virus (EBV)-associated malignancies. NPC is highly metastatic compared to other head and neck carcinomas, and evidence has shown that the metastatic features...
7.
Dochi H, Kondo S, Murata T, Fukuyo M, Nanbo A, Wakae K, et al.
Cancer Sci
. 2022 May;
113(8):2862-2877.
PMID: 35633182
Several epidemiological studies have suggested that Epstein-Barr virus (EBV) lytic infection is essential for the development of nasopharyngeal carcinoma (NPC), as the elevation of antibody titers against EBV lytic proteins...
8.
Kondo S, Okuno Y, Murata T, Dochi H, Wakisaka N, Mizokami H, et al.
Cancer Sci
. 2022 Apr;
113(7):2446-2456.
PMID: 35485636
Nasopharyngeal carcinoma (NPC) is caused by infection with Epstein-Barr virus (EBV) and endemic in certain geographic regions. EBV lytic gene, BALF2, closely associates with viral reactivation and BALF2 gene variation,...
9.
Endo K, Ueno T, Hirai N, Komori T, Nakanishi Y, Kondo S, et al.
Laryngoscope
. 2021 Aug;
132(2):E4.
PMID: 34350990
No abstract available.
10.
Kase K, Kondo S, Wakisaka N, Dochi H, Mizokami H, Kobayashi E, et al.
Microorganisms
. 2021 Apr;
9(3).
PMID: 33804064
Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignancy. The principal oncogene of EBV, latent membrane protein 1 (LMP1), induces the expression of programmed death-ligand 1 (PD-L1), which is an...