Nobuo Kanai
Overview
Explore the profile of Nobuo Kanai including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
379
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Recent Articles
1.
Fujino A, Fuchimoto Y, Mori T, Kano M, Yamada Y, Ohno M, et al.
Stem Cell Res Ther
. 2023 Apr;
14(1):86.
PMID: 37055850
Background: We performed the first autologous oral mucosa-derived epithelial cell sheet transplantation therapy in a patient with refractory postoperative anastomotic stricture in congenital esophageal atresia (CEA) and confirmed its safety....
2.
Kobayashi S, Kanai N, Yamato M, Eguchi S
Regen Ther
. 2022 Jul;
21:157-165.
PMID: 35891710
Introduction: Endoscopic submucosal dissection (ESD) is a minimally invasive treatment for early esophageal cancer. However, large mucosal defects after esophageal ESD result in refractory strictures. In the present study, we...
3.
Fujino A, Fuchimoto Y, Baba Y, Isogawa N, Iwata T, Arai K, et al.
Stem Cell Res Ther
. 2022 Jan;
13(1):35.
PMID: 35090534
Background: Congenital esophageal atresia postoperative anastomotic stricture occurs in 30-50% of cases. Patients with severe dysphagia are treated with endoscopic balloon dilatation (EBD) and/or local injection of steroids, but many...
4.
Kasai Y, Takagi R, Kobayashi S, Owaki T, Yamaguchi N, Fukuda H, et al.
Regen Ther
. 2020 Jan;
14:87-94.
PMID: 31988998
Introduction: Cultured stratified epithelial cell sheets have been clinically utilized as transplantable grafts for the regeneration of epithelial tissues, such as the esophagus, cornea, skin, and intraoral cavity. These cell...
5.
Yamato M, Ohki T, Kanai N, Kondo M, Eguchi S, Sjoqvist S, et al.
Regen Ther
. 2019 Jun;
1:84.
PMID: 31245445
No abstract available.
6.
Takagi R, Kobayashi S, Yamato M, Owaki T, Kasai Y, Hosoi T, et al.
Regen Ther
. 2019 Jun;
1:1-4.
PMID: 31245435
We have utilized patients' own oral mucosa as a cell source for the fabrication of transplantable epithelial cell sheets to treat limbal stem cell deficiency and mucosal defects after endoscopic...
7.
Sjoqvist S, Kasai Y, Shimura D, Ishikawa T, Ali N, Iwata T, et al.
Biochem Biophys Res Commun
. 2019 May;
514(3):706-712.
PMID: 31078263
Extracellular vesicles (EVs), including exosomes, are small membrane-bound particles released by cells. From a therapeutic point of view, EVs can often convey similar biological function as their parent cell. Grafts...
8.
Sjoqvist S, Ishikawa T, Shimura D, Kasai Y, Imafuku A, Bou-Ghannam S, et al.
J Extracell Vesicles
. 2019 Feb;
8(1):1565264.
PMID: 30719240
The oral mucosa exhibits unique regenerative properties, sometimes referred to as foetal-like wound healing. Researchers from our institute have used sheets of oral mucosa epithelial cells (OMECs) for regenerative medicine...
9.
Maruya Y, Kanai N, Kobayashi S, Koshino K, Okano T, Eguchi S, et al.
Regen Ther
. 2018 Oct;
7:24-33.
PMID: 30271849
Objective: Adipose-derived stem cells (ASCs) are capable of multiple differentiation pathways, imparting immunomodulatory effects, and secreting factors that are important for wound healing. These characteristics can be exploited to decrease...
10.
Arakelian L, Kanai N, Dua K, Durand M, Cattan P, Ohki T
Ann N Y Acad Sci
. 2018 Aug;
1434(1):156-163.
PMID: 30088660
For various esophageal diseases, the search for alternative techniques for tissue repair has led to significant developments in basic and translational research in the field of tissue engineering. Applied to...