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Nobuhiro Hakuba

Explore the profile of Nobuhiro Hakuba including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 297
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Recent Articles
1.
Miwa T, Tarui A, Kouga T, Asai Y, Ogita H, Fujikawa T, et al.
Front Cell Neurosci . 2025 Feb; 19:1542164. PMID: 39959464
Age-related hearing loss (ARHL) is a complex condition with genetic, aging, and environmental influences. Sirtuins, particularly SIRT1, are NAD-dependent protein deacetylases critical to aging and stress responses. SIRT1 is modulated...
2.
Nishimura K, Nagahara K, Hakuba N
Ear Nose Throat J . 2023 Feb; :1455613231158802. PMID: 36794806
We describe a right external auditory canal (EAC) recurrent ceruminous pleomorphic adenoma (CPA) accompanied by itching and review the clinical features and histopathology of this disease. A female in her...
3.
Nishimura K, Murofushi T, Hakuba N
Front Neurol . 2022 Nov; 13:1043452. PMID: 36438944
Objective: To present a case of intralabyrinthine schwannoma (ILS) presenting as Ménière's disease diagnosed 4-h delayed gadolinium-enhanced three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D-FLAIR MRI) and treated successfully using...
4.
Uchida Y, Mise K, Suzuki D, Fukunaga Y, Hakuba N, Oishi N, et al.
J Am Med Dir Assoc . 2021 Apr; 22(6):1168-1174. PMID: 33811828
Objectives: To obtain new insights into research questions on how executive function and social interaction would be observed to change after the introduction of hearing aids (HAs) in older people...
5.
Okada M, Hato N, Okada Y, Sato E, Yamada H, Hakuba N, et al.
Auris Nasus Larynx . 2015 May; 42(6):488-91. PMID: 26003880
We report a rare case of hypertrophic cranial pachymeningitis (HCP) associated with invasive Aspergillus mastoiditis. A 63-year-old man with diabetes mellitus underwent mastoidectomy because of chronic discharge from his left...
6.
Hakuba N, Ikemune K, Okada M, Hato N
Am J Otolaryngol . 2014 Dec; 36(2):153-7. PMID: 25433972
Purpose: To present the utility of ambulatory anesthesia using manually assisted ventilation via a facemask for tympanic membrane (TM) regeneration therapy in children. Material And Methods: The study included 10...
7.
Hakuba N, Hato N, Okada M, Mise K, Gyo K
JAMA Otolaryngol Head Neck Surg . 2014 Oct; 141(1):60-6. PMID: 25340882
Importance: The use of growth factors to achieve closure of perforated tympanic membranes (TMs) has recently become popular. However, preoperative factors affecting treatment outcomes have seldom been discussed. Objective: To...
8.
Takagi T, Yoshida T, Okada M, Hata R, Hato N, Gyo K, et al.
Neuroreport . 2014 May; 25(11):807-813. PMID: 24840930
Bone marrow mononuclear cells (BMMCs) are known to enhance recovery from ischemic insults by secreting angiogenic factors and inducing the expression of angiogenic factors from host tissues. Therefore, the transplantation...
9.
Takagi T, Gyo K, Hakuba N, Hyodo J, Hato N
Acta Otolaryngol . 2014 Apr; 134(5):462-7. PMID: 24702226
Conclusions: Potsic's staging system is a clinically useful procedure for evaluating the extent of congenital cholesteatoma (CC). Objectives: We investigated the clinical features, presenting symptoms, and surgical results of CC...
10.
Hakuba N, Tabata Y, Hato N, Fujiwara T, Gyo K
Otol Neurotol . 2014 Feb; 35(3):540-4. PMID: 24518412
Hypothesis: In this developmental research study that aimed to develop tympanic membrane regeneration therapy, we devised a method of sustained bFGF formulation release using gelatin hydrogel in a guinea pig...