Nobue Itasaki
Overview
Explore the profile of Nobue Itasaki including associated specialties, affiliations and a list of published articles.
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28
Citations
1181
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Recent Articles
1.
Knill C, Henderson E, Johnson C, Wah V, Cheng K, Forster A, et al.
FEBS J
. 2023 Aug;
291(2):272-291.
PMID: 37584444
Although gene splicing occurs throughout the body, the phenotype of spliceosomal defects is largely limited to specific tissues. Cerebro-costo-mandibular syndrome (CCMS) is one such spliceosomal disease, which presents as congenital...
2.
Nakamura H, Itasaki N
Dev Growth Differ
. 2023 Jun;
34(4):387-391.
PMID: 37281822
The alar plate of the prosencephalon differentiates into a tectum-like structure when transplanted and integrated into the mesencephalon around 10-somite stage. Homeobox containing gene, en, is expressed in the mesencephalon...
3.
Keeling H, Williams E, Itasaki N
Clin Anat
. 2023 Jun;
37(3):254-269.
PMID: 37265362
Cerebro-costo-mandibular syndrome (CCMS) is a congenital condition with skeletal and orofacial abnormalities that often results in respiratory distress in neonates. The three main phenotypes in the thorax are posterior rib...
4.
Turner B, Mellor C, McElroy C, Bowen N, Gu W, Knill C, et al.
Dev Dyn
. 2022 Sep;
252(2):276-293.
PMID: 36058892
Background: Although splicing is an integral part of the expression of many genes in our body, genetic syndromes with spliceosomal defects affect only specific tissues. To help understand the mechanism,...
5.
Abe-Fukasawa N, Watanabe R, Gen Y, Nishino T, Itasaki N
FEBS J
. 2021 Apr;
288(19):5650-5667.
PMID: 33837641
Three-dimensional (3D) cultures of cancer cells in liquid without extracellular matrix (ECM) offer in vitro models for metastasising conditions such as those in vessels and effusion. However, liquid culturing is...
6.
Turner B, Itasaki N
J Anat
. 2019 Dec;
236(5):931-945.
PMID: 31884688
Ribs are seldom affected by developmental disorders, however, multiple defects in rib structure are observed in the spliceosomal disease cerebro-costo-mandibular syndrome (CCMS). These defects include rib gaps, found in the...
7.
Kumar A, Davies T, Itasaki N
Birth Defects Res
. 2018 Aug;
110(15):1194-1204.
PMID: 30079508
Background: Naturally hypoxic conditions in amniote embryos play important roles in normal development. We previously showed that a hypoxic condition is required to produce a sufficient amount of neural crest...
8.
Abe-Fukasawa N, Otsuka K, Aihara A, Itasaki N, Nishino T
Sci Rep
. 2018 Feb;
8(1):3627.
PMID: 29483620
Cells grown in three-dimensional (3D) cultures are more likely to have native cell-cell and cell-matrix interactions than in 2D cultures that impose mechanical constraints to cells. However, most 3D cultures...
9.
Scully D, Keane E, Batt E, Karunakaran P, Higgins D, Itasaki N
Development
. 2016 May;
143(10):1742-52.
PMID: 27190038
Hypoxia is encountered in either pathological or physiological conditions, the latter of which is seen in amniote embryos prior to the commencement of a functional blood circulation. During the hypoxic...
10.
Barber J, Itasaki N
Gene Expr Patterns
. 2016 Apr;
21(2):97-102.
PMID: 27063263
Hypoxic cellular response is crucial for normal development as well as in pathological conditions in order to tolerate low oxygen. The response is mediated by Hypoxia Inducible Factors (HIFs), where...