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Noah Trac

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Articles 6
Citations 58
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Recent Articles
1.
Lambaren K, Trac N, Fehrenbach D, Madhur M, Chung E
Bioconjug Chem . 2025 Feb; PMID: 39979082
Cardiovascular diseases remain the leading cause of mortality worldwide. Specifically, atherosclerosis is a primary cause of acute cardiac events. However, current therapies mainly focus on lipid-lowering versus addressing the underlying...
2.
Trac N, Chen Z, Oh H, Jones L, Huang Y, Giblin J, et al.
ACS Nano . 2024 Jan; 18(3):2091-2104. PMID: 38212302
Biopsy is the clinical standard for diagnosing lymph node (LN) metastasis, but it is invasive and poses significant risk to patient health. Magnetic resonance imaging (MRI) has been utilized as...
3.
Trac N, Ashraf A, Giblin J, Prakash S, Mitragotri S, Chung E
ACS Nano . 2023 Mar; 17(7):6165-6177. PMID: 36988207
Nanoparticles as drug delivery carriers have benefited diseases, including cancer, since the 1990s, and more recently, their promise to quickly and efficiently be mobilized to fight against global diseases such...
4.
Trac N, Oh H, Jones L, Caliliw R, Ohtake S, Shuch B, et al.
Molecules . 2022 Dec; 27(23). PMID: 36500549
The majority of clear cell renal cell carcinomas (ccRCCs) are characterized by mutations in the Von Hippel−Lindau (VHL) tumor suppressor gene, which leads to the stabilization and accumulation of the...
5.
Chin D, Poon C, Trac N, Wang J, Cook J, Joo J, et al.
Adv Ther (Weinh) . 2021 Jul; 3(3). PMID: 34295964
Atherosclerosis is an inflammatory disease characterized by plaques that can cause sudden myocardial infarction upon rupture. Such rupture-prone plaques have thin fibrous caps due to collagenase degradation, and a noninvasive...
6.
Trac N, Chung E
Exp Biol Med (Maywood) . 2021 May; 246(22):2358-2371. PMID: 33957802
The lymph nodes are major sites of cancer metastasis and immune activity, and thus represent important clinical targets. Although not as well-studied compared to subcutaneous administration, intravenous drug delivery is...
7.
Trac N, Chen L, Zhang A, Liao C, Poon C, Wang J, et al.
J Control Release . 2020 Oct; 329:614-623. PMID: 33011241
Signaling between the CC chemokine receptor 2 (CCR2) with its ligand, monocyte chemoattractant protein-1 (MCP-1) promotes cancer progression by directly stimulating tumor cell proliferation and downregulating the expression of apoptotic...