Nitin J Karandikar
Overview
Explore the profile of Nitin J Karandikar including associated specialties, affiliations and a list of published articles.
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92
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2518
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Recent Articles
1.
Upadhye M, Wilhelm C, Rogers K, Vemulawada C, Borcherding N, Boyden A, et al.
J Neuroinflammation
. 2025 Feb;
22(1):54.
PMID: 40022134
Multiple sclerosis (MS), an autoimmune demyelinating disease of the central nervous system, is modeled in mice as experimental autoimmune encephalomyelitis (EAE). While CD4 T cells, primarily Th1 and Th17 subsets,...
2.
Zeng Q, Guo H, Tang N, Renavikar P, Karandikar N, Lovett-Racke A, et al.
J Biomed Sci
. 2025 Feb;
32(1):26.
PMID: 39972304
Background: The HECT E3 ubiquitin ligase Nedd4 has been shown to positively regulate T cell responses, but its role in T helper (Th) cell differentiation and autoimmunity is unknown. Th17...
3.
Vemulawada C, Renavikar P, Crawford M, Steward-Tharp S, Karandikar N
J Immunol
. 2024 Apr;
212(11):1722-1732.
PMID: 38607279
An imbalance between proinflammatory and regulatory processes underlies autoimmune disease pathogenesis. We have shown that acute relapses of multiple sclerosis are characterized by a deficit in the immune suppressive ability...
4.
Wilhelm C, Upadhye M, Eschbacher K, Karandikar N, Boyden A
J Immunol
. 2023 Aug;
211(6):944-953.
PMID: 37548478
The pathogenic role B cells play in multiple sclerosis is underscored by the success of B cell depletion therapies. Yet, it remains unclear how B cells contribute to disease, although...
5.
Chopra S, Karandikar N, Holman C
Am J Clin Pathol
. 2023 Jun;
160(4):331-334.
PMID: 37289433
Objectives: We evaluated and compared the peripheral blood findings in patients with acute COVID-19 vs other viral respiratory infections. Methods: We retrospectively reviewed peripheral blood counts and smear morphology in...
6.
Crawford M, Borcherding N, Karandikar N
PLoS One
. 2023 Apr;
18(4):e0285166.
PMID: 37115755
CD4+ T-helper 17 (Th17) T cells are a key population in protective immunity during infection and in self-tolerance/autoimmunity. Through the secretion of IL-17, Th17 cells act in promotion of inflammation...
7.
Farooqui M, Ortega-Gutierrez S, Hernandez K, Torres V, Dajles A, Zevallos C, et al.
Ann Clin Transl Neurol
. 2022 Dec;
10(2):276-291.
PMID: 36579400
Objective: Despite successful endovascular therapy, a proportion of stroke patients exhibit long-term functional decline, regardless of the cortical reperfusion. Our objective was to evaluate the early activation of the adaptive...
8.
Snyder J, Radaelli E, Goeken A, Businga T, Boyden A, Karandikar N, et al.
Vet Pathol
. 2022 Feb;
59(3):498-505.
PMID: 35130806
Intravascular (IV) perfusion of tissue fixative is commonly used in the field of neuroscience as the central nervous system tissues are exquisitely sensitive to handling and fixation artifacts which can...
9.
Brate A, Boyden A, Jensen I, Badovinac V, Karandikar N
J Immunol
. 2021 Feb;
206(6):1151-1160.
PMID: 33558376
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the CNS. We have previously demonstrated that CNS-specific CD8 T cells possess a disease-suppressive function in MS and variations of its...
10.
Chopra S, Dunham T, Syrbu S, Karandikar N, Darbro B, Holman C
Am J Clin Pathol
. 2021 Jan;
156(2):198-204.
PMID: 33437993
Objectives: We sought to investigate the clinical utility of flow cytometry (FC) and fluorescence in situ hybridization (FISH) in the workup of myeloma. Methods: We retrospectively reviewed the reports of...