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Nitin Dixit

Explore the profile of Nitin Dixit including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 133
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Recent Articles
1.
Salamat-Miller N, Turner M, Bandekar A, Dixit N, Jochim E, Mangum B, et al.
World J Pediatr . 2022 Nov; 19(1):58-67. PMID: 36344872
Background: Recombinant human (rh)IGF-1/IGFBP-3 protein complex, administered as a continuous intravenous infusion in preterm infants, is being studied for the prevention of complications of prematurity. Methods: We conducted in vitro...
2.
Siddiqui A, Agarwal M, Dixit N
Indian J Tuberc . 2022 Jan; 69(1):120-122. PMID: 35074145
No abstract available.
3.
Dixit N, Salamat-Miller N, Salinas P, Taylor K, Basu S
J Pharm Sci . 2016 Apr; 105(5):1657-1666. PMID: 27032893
This study investigated the root cause behind an observed free fatty acid particle formation and resulting Polysorbate 20 (PS20) loss for a sulfatase drug product upon long-term storage at 5...
4.
Hartl E, Dixit N, Besheer A, Kalonia D, Winter G
Eur J Pharm Biopharm . 2013 May; 85(3 Pt A):781-9. PMID: 23685354
In a quest to elucidate the mechanism by which hydroxypropyl β-cyclodextrin (HPβCD) stabilizes antibodies against shaking stress, two heavily debated hypotheses exist, namely that stabilization is due to HPβCD's surface...
5.
Dixit N, Maloney K, Kalonia D
Pharm Res . 2013 Apr; 30(7):1848-59. PMID: 23568525
Purpose: To study the effect of three nonionic surfactants on the protein-silicone oil interactions. Methods: The adsorption of Tween® 80, Pluronic® F68 and Tween® 20 at the silicone oil/water interface...
6.
Dixit N, Zeng D, Kalonia D
Int J Pharm . 2012 Sep; 439(1-2):317-23. PMID: 22985604
Binding of a surfactant to proteins can affect their physicochemical stability and solubility in a formulation. The extent of the effect depends on the binding stoichiometry. In this study, we...
7.
Dixit N, Maloney K, Kalonia D
AAPS PharmSciTech . 2012 Sep; 13(4):1116-9. PMID: 22936408
No abstract available.
8.
Dixit N, Maloney K, Kalonia D
Int J Pharm . 2012 Mar; 429(1-2):158-67. PMID: 22429889
There is evidence in the literature that silicone oil, a lubricant, can induce aggregation in protein formulations delivered through prefilled syringes. Surfactants are commonly used to minimize protein-silicone oil and...
9.
Kumar V, Dixit N, Zhou L, Fraunhofer W
Int J Pharm . 2011 Oct; 421(1):82-93. PMID: 21959107
The purpose of this work was to determine the nature of long and short-range forces governing protein aggregation kinetics at low and high concentrations for a monoclonal antibody (IgG1) and...
10.
Dixit N, Maloney K, Kalonia D
Int J Pharm . 2011 Apr; 412(1-2):20-7. PMID: 21497645
In this study, we have used quartz crystal microbalance (QCM) to quantitate the adsorption of a protein on silicone oil coated surfaces as a function of protein concentration, pH and...