Nishit Doshi
Overview
Explore the profile of Nishit Doshi including associated specialties, affiliations and a list of published articles.
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15
Citations
638
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Recent Articles
1.
Gupta V, Hwang B, Doshi N, Banerjee A, Anselmo A, Mitragotri S
Ann Biomed Eng
. 2016 Feb;
44(6):1993-2007.
PMID: 26864536
A major disadvantage associated with current diabetes therapy is dependence on injectables for long-term disease management. In addition to insulin, incretin hormone replacement therapies including exenatide have added a new...
2.
Hwang B, Doshi N, Tsai K, Mitragotri S
Drug Deliv Transl Res
. 2015 Mar;
2(5):297-304.
PMID: 25787172
Collection of cytosolic proteins from cells and tissues is the first and essential step in many bioanalytical assays that play a key role in medical applications such as diagnostics, theranostics,...
3.
Gupta V, Hwang B, Lee J, Anselmo A, Doshi N, Mitragotri S
J Control Release
. 2013 Sep;
172(3):753-62.
PMID: 24035976
One of the major challenges faced by therapeutic polypeptides remains their invasive route of delivery. Oral administration offers a potential alternative to injections; however, this route cannot be currently used...
4.
Gupta V, Hwang B, Doshi N, Mitragotri S
J Control Release
. 2013 May;
172(2):541-9.
PMID: 23680288
Delivery of therapeutic macromolecules is limited by the physiological limitations of the gastrointestinal tract including poor intestinal permeability, low pH and enzymatic activity. Several permeation enhancers have been proposed to...
5.
Gupta V, Doshi N, Mitragotri S
PLoS One
. 2013 Mar;
8(2):e57136.
PMID: 23483881
Objectives: Caco-2 monolayers are one of the most widely used in vitro models for prediction of intestinal permeability of therapeutic molecules. However, the conventional Caco-2 monolayer model has several drawbacks...
6.
Doshi N, Orje J, Molins B, Smith J, Mitragotri S, Ruggeri Z
Adv Mater
. 2012 May;
24(28):3864-9.
PMID: 22641451
No abstract available.
7.
Kirch J, Guenther M, Doshi N, Schaefer U, Schneider M, Mitragotri S, et al.
J Control Release
. 2012 Jan;
159(1):128-34.
PMID: 22226774
The fate of inhaled particles after deposition onto the pulmonary mucosa is far from being solved, in particular with respect to mucociliary clearance and mucus penetration. Due to the fact...
8.
Kolhar P, Doshi N, Mitragotri S
Small
. 2011 Jun;
7(14):2094-100.
PMID: 21695782
Delivery of drugs into the cellular cytoplasm of target cells represents a major hurdle in treating various diseases. This challenge can be addressed by encapsulation of drugs onto or within...
9.
Yoo J, Doshi N, Mitragotri S
Adv Drug Deliv Rev
. 2011 May;
63(14-15):1247-56.
PMID: 21605607
Recent studies have led to significant advances in understanding the impact of key drug carrier properties such as size, surface chemistry and shape on their performance. Converting this knowledge into...
10.
Yoo J, Doshi N, Mitragotri S
Macromol Rapid Commun
. 2011 May;
31(2):142-8.
PMID: 21590886
Targeting, internalization, and intracellular trafficking of carriers are key processes in drug delivery to endothelial cells. We synthesized PLGA particles with spherical and elliptical disk geometries and investigated the effect...