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Nishad Jayasundara

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Articles 51
Citations 418
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Recent Articles
1.
Carrothers S, Trevisan R, Jayasundara N, Pelletier N, Weeks E, Meyer J, et al.
Sci Rep . 2025 Jan; 15(1):3033. PMID: 39856074
Human exposure to polycyclic aromatic hydrocarbons (PAH) is a significant public health problem that will worsen with a warming climate and increased large-scale wildfires. Here, we characterize an epigenetic memory...
2.
Harishchandra A, Di Giulio R, Jayasundara N
Environ Sci Technol . 2024 Nov; 58(47):20859-20872. PMID: 39552013
Environmental contaminants pose a significant selection pressure across taxa, potentiating evolved resistance to chemicals. However, rapid evolution may alter molecular and physiological homeostasis leading to trade-offs. To elucidate molecular underpinnings...
3.
Dilrukshi K, Merutka I, Chernick M, Rohrbach S, Babich R, Withanage N, et al.
Ecotoxicol Environ Saf . 2024 Nov; 287:117296. PMID: 39536556
Mixtures of chemical contaminants can pose a significant health risk to humans and wildlife, even at levels considered safe for each individual chemical. There is a critical need to develop...
4.
Carrothers S, Trevisan R, Jayasundara N, Pelletier N, Weeks E, Meyer J, et al.
bioRxiv . 2024 Aug; PMID: 39185187
Human exposure to polycyclic aromatic hydrocarbons (PAH) is a significant and growing public health problem. Frequent, high dose exposures are likely to increase due to a warming climate and increased...
5.
Guelfo J, Ferguson P, Beck J, Chernick M, Doria-Manzur A, Faught P, et al.
Nat Commun . 2024 Jul; 15(1):5548. PMID: 38977667
Lithium-ion batteries (LiBs) are used globally as a key component of clean and sustainable energy infrastructure, and emerging LiB technologies have incorporated a class of per- and polyfluoroalkyl substances (PFAS)...
6.
Gunasekara T, Herath C, De Silva P, Jayasundara N
Children (Basel) . 2024 Jan; 11(1). PMID: 38255329
Normalization of urinary biomarkers of kidney injury is a common practice in clinical and research settings to account for variations in urine concentration, and urinary creatinine is often used as...
7.
Sandamini P, Jayasinghe S, De Silva P, Jayasundara N
J Trace Elem Med Biol . 2023 Dec; 82:127367. PMID: 38134492
Background: High fluoride exposure is increasingly discussed attributing to kidney injury as a causative factor. Depending on geochemistry, differential fluoride levels in drinking water are identified in different regions in...
8.
Babich R, Merutka I, Craig E, Harichandara A, De Silva P, Gunasekara T, et al.
Sci Total Environ . 2023 Dec; 912:169271. PMID: 38114029
Investigation of developmental molecular events following exposure to environmentally relevant agrochemical mixtures is critical to predicting their potential long-term ecological and human health risks. Here, we sought to uncover transcriptomic...
9.
Gunasekara T, De Silva P, Chandana E, Jayasinghe S, Herath C, Siribaddana S, et al.
Pediatr Nephrol . 2023 Dec; 39(5):1469-1480. PMID: 38085354
Background: Environmental fluoride exposure at elevated levels is potentially linked to kidney injury, and may contribute to chronic kidney disease of uncertain etiology (CKDu) as a risk factor. However, this...
10.
Jasperse L, Di Giulio R, Jayasundara N
Environ Sci Technol . 2023 Oct; 57(42):15806-15815. PMID: 37818763
Shifts in key physiological processes can confer resistance to chemical pollutants. However, these adaptations may come with certain trade-offs, such as altered energy metabolic processes, as evident in Atlantic killifish...