Nirmal Rajasekaran
Overview
Explore the profile of Nirmal Rajasekaran including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
292
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Recent Articles
11.
Bach D, Kim D, Bae S, Kim W, Hong J, Lee H, et al.
Mol Ther Nucleic Acids
. 2018 Jun;
11:455-467.
PMID: 29858080
Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are used clinically as target therapies for lung cancer patients, but the occurrence of acquired drug resistance limits their efficacy. Nicotinamide N-methyltransferase...
12.
Lim D, Rajasekaran N, Lee D, Kim N, Jung H, Hong S, et al.
ACS Appl Mater Interfaces
. 2017 Aug;
9(37):31543-31556.
PMID: 28853284
Nanodiamonds have been discovered as a new exogenous material source in biomedical applications. As a new potent form of nanodiamond (ND), polyamidoamine-decorated nanodiamonds (PAMAM-NDs) were prepared for E7 or E6...
13.
Rajasekaran N, Jung H, Bae S, Chelakkot C, Hong S, Choi J, et al.
Neoplasia
. 2017 Aug;
19(10):735-749.
PMID: 28843398
Toxicity and resistance remain major challenges for advanced or recurrent cervical cancer therapies, as treatment requires high doses of chemotherapeutic agents. Restoration of TP53 and hypophosphorylated-retinoblastoma (pRB) proteins by human...
14.
Chelakkot C, Ghim J, Rajasekaran N, Choi J, Kim J, Jang M, et al.
Sci Rep
. 2017 May;
7(1):1573.
PMID: 28484281
Ulcerative colitis is a multi-factorial disease involving a dysregulated immune response. Disruptions to the intestinal epithelial barrier and translocation of bacteria, resulting in inflammation, are common in colitis. The mechanisms...
15.
Lee J, Kim S, Lee H, Hong S, Rajasekaran N, Wang L, et al.
Int J Oncol
. 2016 Dec;
50(1):272-282.
PMID: 27922669
SMAD4 is a tumor suppressor that is frequently inactivated in many types of cancer. The role of abnormal expression of SMAD4 has been reported in developmental processes and the progression...
16.
Rajasekaran N, Oh M, Kim S, Kim S, Kim Y, Choi H, et al.
J Vis Exp
. 2015 Oct;
(104).
PMID: 26484710
ddPCR is a highly sensitive PCR method that utilizes a water-oil emulsion system. Using a droplet generator, an extracted nucleic acid sample is partitioned into ~20,000 nano-sized, water-in-oil droplets, and...
17.
Jung H, Rajasekaran N, Ju W, Shin Y
J Clin Med
. 2015 Aug;
4(5):1126-55.
PMID: 26239469
Human papillomaviruses (HPVs) are small DNA viruses; some oncogenic ones can cause different types of cancer, in particular cervical cancer. HPV-associated carcinogenesis provides a classical model system for RNA interference...
18.
Jung H, Rajasekaran N, Song S, Kim Y, Hong S, Choi H, et al.
Int J Mol Sci
. 2015 Jun;
16(6):12243-60.
PMID: 26035754
The functional inactivation of TP53 and Rb tumor suppressor proteins by the HPV-derived E6 and E7 oncoproteins is likely an important step in cervical carcinogenesis. We have previously shown siRNA...