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Nina Kemppainen

Explore the profile of Nina Kemppainen including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 468
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Recent Articles
1.
Saadmaan G, Hall A, Ngandu T, Kemppainen N, Mangialasche F, Wittenberg G, et al.
Eur J Neurol . 2024 Aug; 31(12):e16436. PMID: 39132977
Background And Purpose: This study evaluated associations of brain amyloid with 2-year objective and subjective cognitive measures in a trial-ready older general population at risk for dementia. Methods: Forty-eight participants...
2.
Saadmaan G, Dalmasso M, Ramirez A, Hiltunen M, Kemppainen N, Lehtisalo J, et al.
Alzheimers Dement . 2024 Apr; 20(6):4345-4350. PMID: 38647197
Introduction: We assessed a genetic risk score for Alzheimer's disease (AD-GRS) and apolipoprotein E (APOE4) in an exploratory neuroimaging substudy of the FINGER trial. Methods: 1260 at-risk older individuals without...
3.
Rydstrom A, Stephen R, Kareholt I, Mattsson A, Ngandu T, Lehtisalo J, et al.
Gerontology . 2023 Apr; 69(8):972-985. PMID: 37071974
Introduction: Mechanisms underlying the positive association between occupational mental demands and late-life cognition are poorly understood. The objective of this study was to assess whether the association between occupational complexity...
4.
Stephen R, Ngandu T, Liu Y, Peltonen M, Antikainen R, Kemppainen N, et al.
J Gerontol A Biol Sci Med Sci . 2021 May; 76(8):1407-1414. PMID: 33970268
The CAIDE (Cardiovascular Risk Factors, Aging and Dementia) Risk Score is a validated tool estimating dementia risk. It was previously associated with imaging biomarkers. However, associations between dementia risk scores...
5.
Sandebring-Matton A, Goikolea J, Bjorkhem I, Paternain L, Kemppainen N, Laatikainen T, et al.
Alzheimers Res Ther . 2021 Mar; 13(1):56. PMID: 33676572
Background: 27-Hydroxycholesterol (27-OH), the main circulating oxysterol in humans and the potential missing link between peripheral hypercholesterolemia and Alzheimer's disease (AD), has not been investigated previously in relation to cognition...
6.
Stephen R, Solomon A, Ngandu T, Levalahti E, Rinne J, Kemppainen N, et al.
J Alzheimers Dis . 2020 Sep; 78(1):75-86. PMID: 32925045
Background: Early pathological changes in white matter microstructure can be studied using the diffusion tensor imaging (DTI). It is not only important to study these subtle pathological changes leading to...
7.
Pekkala T, Hall A, Ngandu T, van Gils M, Helisalmi S, Hanninen T, et al.
Front Aging Neurosci . 2020 Aug; 12:228. PMID: 32848707
The importance of early interventions in Alzheimer's disease (AD) emphasizes the need to accurately and efficiently identify at-risk individuals. Although many dementia prediction models have been developed, there are fewer...
8.
Pekkala T, Hall A, Mangialasche F, Kemppainen N, Mecocci P, Ngandu T, et al.
J Alzheimers Dis . 2020 Jul; 76(4):1243-1248. PMID: 32623394
We explored the association of type 2 diabetes related blood markers with brain amyloid accumulation on PiB-PET scans in 41 participants from the FINGER PET sub-study. We built logistic regression...
9.
Honkanen E, Kemppainen N, Noponen T, Seppanen M, Joutsa J, Kaasinen V
Clin Neuropharmacol . 2019 Jul; 42(5):181-183. PMID: 31361666
Objective: The objective of this study was to report long-lasting effects of bupropion on brain dopamine transporter (DAT) in a patient with depression and parkinsonism. Methods: The patient was a...
10.
Stephen R, Liu Y, Ngandu T, Antikainen R, Hulkkonen J, Koikkalainen J, et al.
Alzheimers Res Ther . 2019 Jun; 11(1):53. PMID: 31164160
Background: The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) was a multicenter randomized controlled trial that reported beneficial effects on cognition for a 2-year multimodal intervention...