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Nilton Nascimento Santos-Junior

Explore the profile of Nilton Nascimento Santos-Junior including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Catalao C, de Oliveira Souza A, Santos-Junior N, da Costa L, Dos Santos J, Alberici L, et al.
Mol Cell Biochem . 2022 May; 477(11):2657-2667. PMID: 35604517
Sepsis causes overproduction of inflammatory cytokines, organ dysfunction, and cognitive impairment in survivors. In addition to inflammation, metabolic changes occur according to the stage and severity of the disease. Understanding...
2.
Ribeiro A, da Silva T, Santos-Junior N, Castania J, Fazan Jr R, Salgado H
BMC Oral Health . 2021 Oct; 21(1):515. PMID: 34635094
Background: We previously reported that periodontal disease (PD) induces high arterial pressure variability (APV) consistent with sympathetic overactivity and elicits myocardial inflammation in Balb/c mice. However, it is unknown whether...
3.
Brognara F, Castania J, Ribeiro A, Santos-Junior N, Salgado H
Front Physiol . 2021 Oct; 12:745285. PMID: 34616312
Evidence indicates that the activation of the parasympathetic branch of the autonomic nervous system may be effective in treating inflammatory diseases. Previously, we have described that baroreflex activation displays anti-inflammatory...
4.
da Costa L, Santos-Junior N, Catalao C, Rocha M
Mol Neurobiol . 2021 Jan; 58(5):2133-2144. PMID: 33415683
Sepsis promotes an inflammatory state in the central nervous system (CNS) that may cause autonomic, cognitive, and endocrine changes. Microglia, a resident immune cell of the CNS, is activated in...
5.
Catalao C, Santos-Junior N, da Costa L, Souza A, Carnio E, Sebollela A, et al.
Neurotox Res . 2020 Jun; 38(4):871-886. PMID: 32524380
Sepsis-associated encephalopathy causes brain dysfunction that can result in cognitive impairments in sepsis survivor patients. In previous work, we showed that simvastatin attenuated oxidative stress in brain structures related to...
6.
Ribeiro A, Santos-Junior N, Luiz J, Oliveira M, Kanashiro A, Taira T, et al.
Sci Rep . 2020 Apr; 10(1):6891. PMID: 32327711
The present study examined the hemodynamics [arterial pressure (AP), AP variability (APV), heart rate (HR), and heart rate variability (HRV)], cardiac function (echocardiographycally), and myocardial inflammation in Balb/c mice submitted...
7.
Cazuza R, Santos-Junior N, da Costa L, Catalao C, Mendes-Gomes J, da Rocha M, et al.
J Neuroimmunol . 2020 Mar; 342:577198. PMID: 32120082
Sepsis-associated encephalopathy (SAE) is a significant problem in patients with sepsis, and it is associated with a decrease in cognitive and sensitivity capability induced by systemic inflammation. SAE is implicated...
8.
Catalao C, Souza A, Santos-Junior N, da Silva S, da Costa L, Alberici L, et al.
Brain Res . 2019 Aug; 1724:146408. PMID: 31465772
In hydrocephalus, the progressive accumulation of cerebrospinal fluid (CSF) causes dilatation of the lateral ventricles affecting the third ventricle and diencephalic structures such as the hypothalamus. These structures play a...
9.
Amarilla A, Santos-Junior N, Figueiredo M, Luiz J, Fumagalli M, Colon D, et al.
J Infect Dis . 2019 Feb; 219(12):2015-2025. PMID: 30715407
Rocio virus (ROCV) is a highly neuropathogenic mosquito-transmitted flavivirus responsible for an unprecedented outbreak of human encephalitis during 1975-1976 in Sao Paulo State, Brazil. Previous studies have shown an increased...
10.
de Oliveira Souza A, Couto-Lima C, Catalao C, Santos-Junior N, Dos Santos J, da Rocha M, et al.
Neurotoxicology . 2018 Dec; 70:154-160. PMID: 30502405
Several studies have shown the protective effects of dietary enrichment of omega-3 (ω-3) long-chain fatty acids in several animal models of neurodegenerative diseases. Here we investigate if eicosapentaenoic (EPA) and...