Nikolay P Kandul
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Explore the profile of Nikolay P Kandul including associated specialties, affiliations and a list of published articles.
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16
Citations
465
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Recent Articles
1.
Li M, Kandul N, Sun R, Yang T, Benetta E, Brogan D, et al.
Elife
. 2024 Jan;
12.
PMID: 38289340
Each year, hundreds of millions of people are infected with arboviruses such as dengue, yellow fever, chikungunya, and Zika, which are all primarily spread by the notorious mosquito . Traditional...
2.
Davydova S, Liu J, Kandul N, Braswell W, Akbari O, Meccariello A
Sci Rep
. 2023 Nov;
13(1):19866.
PMID: 37964160
Tephritid fruit fly pests pose an increasing threat to the agricultural industry due to their global dispersion and a highly invasive nature. Here we showcase the feasibility of an early-detection...
3.
Li M, Kandul N, Sun R, Yang T, Benetta E, Brogan D, et al.
bioRxiv
. 2023 May;
PMID: 37131747
Each year, hundreds of millions of people are infected with arboviruses such as dengue, yellow fever, chikungunya, and Zika, which are all primarily spread by the notorious mosquito . Traditional...
4.
Verkuijl S, Gonzalez E, Li M, Ang J, Kandul N, Anderson M, et al.
Nat Commun
. 2022 Nov;
13(1):7145.
PMID: 36414618
CRISPR/Cas gene drives can bias transgene inheritance through different mechanisms. Homing drives are designed to replace a wild-type allele with a copy of a drive element on the homologous chromosome....
5.
Gamez S, Chaverra-Rodriguez D, Buchman A, Kandul N, Mendez-Sanchez S, Bennett J, et al.
Nat Commun
. 2021 Dec;
12(1):7202.
PMID: 34893590
CRISPR-based genetic engineering tools aimed to bias sex ratios, or drive effector genes into animal populations, often integrate the transgenes into autosomal chromosomes. However, in species with heterogametic sex chromsomes...
6.
Kandul N, Liu J, Akbari O
CRISPR J
. 2021 Nov;
4(6):822-835.
PMID: 34735288
Releases of sterile males are the gold standard for many insect population control programs, and precise sex sorting to remove females prior to male releases is essential to the success...
7.
Kandul N, Belikoff E, Liu J, Buchman A, Li F, Yamamoto A, et al.
CRISPR J
. 2021 Oct;
4(5):739-751.
PMID: 34661429
Originally from Asia, Matsumura is a global pest of economically important soft-skinned fruits. Also commonly known as spotted wing drosophila, it is largely controlled through repeated applications of broad-spectrum insecticides...
8.
Li M, Yang T, Bui M, Gamez S, Wise T, Kandul N, et al.
Nat Commun
. 2021 Sep;
12(1):5374.
PMID: 34508072
The mosquito Aedes aegypti is the principal vector for arboviruses including dengue/yellow fever, chikungunya, and Zika virus, infecting hundreds of millions of people annually. Unfortunately, traditional control methodologies are insufficient,...
9.
Kandul N, Liu J, Bennett J, Marshall J, Akbari O
Elife
. 2021 Mar;
10.
PMID: 33666174
Homing-based gene drives, engineered using CRISPR/Cas9, have been proposed to spread desirable genes throughout populations. However, invasion of such drives can be hindered by the accumulation of resistant alleles. To...
10.
Kandul N, Liu J, Hsu A, Hay B, Akbari O
Nat Commun
. 2020 May;
11(1):2106.
PMID: 32355156
Here, we describe a drug-inducible genetic system for insect sex-separation that demonstrates proof-of-principle for positive sex selection in D. melanogaster. The system exploits the toxicity of commonly used broad-spectrum antibiotics...