Nikolai A Lohr
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Explore the profile of Nikolai A Lohr including associated specialties, affiliations and a list of published articles.
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6
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51
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Recent Articles
1.
Lohr N, Platz L, Hoffmeister D, Muller M
Curr Opin Chem Biol
. 2024 Aug;
82:102510.
PMID: 39128325
Mushroom-forming fungi exhibit a distinctive ecology, which is unsurprisingly also reflected in unique and divergent biosynthetic pathways. We review this phenomenon through the lens of the polyketide metabolism, where mushrooms...
2.
Platz L, Lohr N, Girkens M, Eisen F, Braun K, Fessner N, et al.
Angew Chem Int Ed Engl
. 2024 Jul;
63(42):e202407425.
PMID: 38963262
Bioactive dimeric (pre-)anthraquinones are ubiquitous in nature and are found in bacteria, fungi, insects, and plants. Their biosynthesis via oxidative phenol coupling (OPC) is catalyzed by cytochrome P450 enzymes, peroxidases,...
3.
Lohr N, Rakhmanov M, Wurlitzer J, Lackner G, Gressler M, Hoffmeister D
Fungal Biol Biotechnol
. 2023 Aug;
10(1):17.
PMID: 37542286
Background: Non-reducing polyketide synthases (NR-PKSs) account for a major share of natural product diversity produced by both Asco- and Basidiomycota. The present evolutionary diversification into eleven clades further underscores the...
4.
Lohr N, Urban M, Eisen F, Platz L, Huttel W, Gressler M, et al.
Chembiochem
. 2022 Dec;
24(3):e202200649.
PMID: 36507600
The nonreducing iterative type I polyketide synthases (NR-PKSs) CoPKS1 and CoPKS4 of the webcap mushroom Cortinarius odorifer share 88 % identical amino acids. CoPKS1 almost exclusively produces a tricyclic octaketide...
5.
Lohr N, Eisen F, Thiele W, Platz L, Motter J, Huttel W, et al.
Angew Chem Int Ed Engl
. 2022 Feb;
61(24):e202116142.
PMID: 35218274
(Pre-)anthraquinones are widely distributed natural compounds and occur in plants, fungi, microorganisms, and animals, with atrochrysone (1) as the key biosynthetic precursor. Chemical analyses established mushrooms of the genus Cortinarius-the...
6.
Gressler M, Lohr N, Schafer T, Lawrinowitz S, Seibold P, Hoffmeister D
Nat Prod Rep
. 2021 Jan;
38(4):702-722.
PMID: 33404035
Covering: up to September 2020 Mushroom-forming fungi of the division Basidiomycota have traditionally been recognised as prolific producers of structurally diverse and often bioactive secondary metabolites, using the methods of...