Nikki van Teijlingen Bakker
Overview
Explore the profile of Nikki van Teijlingen Bakker including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
363
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Recent Articles
1.
Castoldi A, Sanin D, van Teijlingen Bakker N, Aguiar C, de Brito Monteiro L, Rana N, et al.
iScience
. 2023 Sep;
26(10):107719.
PMID: 37674984
Little is known about the effects of high-fat diet (HFD)-induced obesity on resident colonic lamina propria (LP) macrophages (LPMs) function and metabolism. Here, we report that obesity and diabetes resulted...
2.
Caputa G, Matsushita M, Sanin D, Kabat A, Edwards-Hicks J, Grzes K, et al.
Cell Metab
. 2022 May;
34(5):747-760.e6.
PMID: 35508110
Adipose tissue (AT) plays a central role in systemic metabolic homeostasis, but its function during bacterial infection remains unclear. Following subcutaneous bacterial infection, adipocytes surrounding draining lymph nodes initiated a...
3.
de Brito Monteiro L, Prodonoff J, de Aguiar C, Correa-da-Silva F, Castoldi A, van Teijlingen Bakker N, et al.
Diabetes
. 2022 Apr;
71(7):1546-1561.
PMID: 35377454
Obesity is a major concern for global health care systems. Systemic low-grade inflammation in obesity is a major risk factor for insulin resistance. Leptin is an adipokine secreted by the...
4.
Castoldi A, Monteiro L, van Teijlingen Bakker N, Sanin D, Rana N, Corrado M, et al.
Nat Commun
. 2020 Aug;
11(1):4107.
PMID: 32796836
Foamy macrophages, which have prominent lipid droplets (LDs), are found in a variety of disease states. Toll-like receptor agonists drive triacylglycerol (TG)-rich LD development in macrophages. Here we explore the...
5.
van Teijlingen Bakker N, Pearce E
Immunol Rev
. 2020 Apr;
295(1):54-67.
PMID: 32242952
We have only recently started to appreciate the extent to which immune cell activation involves significant changes in cellular metabolism. We are now beginning to understand how commitment to specific...
6.
Qiu J, Villa M, Sanin D, Buck M, OSullivan D, Ching R, et al.
Cell Rep
. 2019 May;
27(7):2063-2074.e5.
PMID: 31091446
Competition for nutrients like glucose can metabolically restrict T cells and contribute to their hyporesponsiveness during cancer. Metabolic adaptation to the surrounding microenvironment is therefore key for maintaining appropriate cell...
7.
Sanin D, Matsushita M, Geltink R, Grzes K, van Teijlingen Bakker N, Corrado M, et al.
Immunity
. 2018 Dec;
49(6):1021-1033.e6.
PMID: 30566880
Metabolic engagement is intrinsic to immune cell function. Prostaglandin E2 (PGE2) has been shown to modulate macrophage activation, yet how PGE2 might affect metabolism is unclear. Here, we show that...