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Nikita V Ivanisenko

Explore the profile of Nikita V Ivanisenko including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 336
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Recent Articles
1.
Konig C, Ivanisenko N, Ivanisenko V, Kulms D, Lavrik I
Commun Biol . 2025 Jan; 8(1):4. PMID: 39753884
Extrinsic apoptotic network is driven by Death Ligand (DL)-mediated activation of procaspase-8. Recently, we have developed the first-in class small molecule, FLIPinB, which specifically targets the key regulator of extrinsic...
2.
Burakova L, Ivanisenko N, Rukosueva N, Ivanisenko V, Vysotski E
Life (Basel) . 2024 Nov; 14(11). PMID: 39598306
Here, we describe (1) the AlphaFold-based structural modeling approach to identify amino acids of the photoprotein berovin that are crucial for coelenterazine binding, and (2) the production and characterization of...
3.
Lavrik I, Ivanisenko N
Trends Cell Biol . 2024 Nov; 34(12):986-987. PMID: 39567280
Apoptosis, a well-established program of cell death, is fundamental to all multicellular organisms. Recent studies of apoptosis initiation events using proteome-wide cellular thermal shift assay (CETSA) have revealed a novel...
4.
Hillert-Richter L, Konig C, Ivanisenko N, Reinhold D, Lavrik I
Front Cell Dev Biol . 2024 Oct; 12:1471216. PMID: 39403127
Death receptor (DR) networks are controlled by the assembly of the Death-Inducing Signaling Complex (DISC) and complex II. The family of small molecules FLIPins (FLIP interactors) were developed to target...
5.
Konig C, Ivanisenko N, Hillert-Richter L, Namjoshi D, Natu K, Espe J, et al.
Cell Chem Biol . 2024 Jul; 31(11):1969-1985.e6. PMID: 39053461
Activation of procaspase-8 in the death effector domain (DED) filaments of the death-inducing signaling complex (DISC) is a key step in apoptosis. In this study, a rationally designed cell-penetrating peptide,...
6.
Ivanisenko N, Shashkova T, Shevtsov A, Sindeeva M, Umerenkov D, Kardymon O
Nucleic Acids Res . 2024 May; 52(W1):W533-W539. PMID: 38742639
Prediction of conformational B-cell epitopes is a crucial task in vaccine design and development. In this work, we have developed SEMA 2.0, a user-friendly web platform that enables the research...
7.
Wohlfromm F, Ivanisenko N, Pietkiewicz S, Konig C, Seyrek K, Kahne T, et al.
Oncogene . 2024 May; 43(25):1955-1971. PMID: 38730267
Procaspase-8 is a key mediator of death receptor (DR)-mediated pathways. Recently, the role of post-translational modifications (PTMs) of procaspase-8 in controlling cell death has received increasing attention. Here, using mass...
8.
Seyrek K, Ivanisenko N, Konig C, Lavrik I
Trends Cell Biol . 2024 Feb; 34(9):728-741. PMID: 38336591
The importance of post-translational modifications (PTMs), particularly O-GlcNAcylation, of cytoplasmic proteins in apoptosis has been neglected for quite a while. Modification of cytoplasmic proteins by a single N-acetylglucosamine sugar is...
9.
Antropova E, Khlebodarova T, Demenkov P, Volianskaia A, Venzel A, Ivanisenko N, et al.
J Integr Bioinform . 2023 Nov; 20(3). PMID: 37978846
Hepatocellular carcinoma (HCC) has been associated with hepatitis C viral (HCV) infection as a potential risk factor. Nonetheless, the precise genetic regulatory mechanisms triggered by the virus, leading to virus-induced...
10.
Umerenkov D, Nikolaev F, Shashkova T, Strashnov P, Sindeeva M, Shevtsov A, et al.
Bioinformatics . 2023 Nov; 39(11). PMID: 37935419
Motivation: Accurate prediction of change in protein stability due to point mutations is an attractive goal that remains unachieved. Despite the high interest in this area, little consideration has been...