Nikhil R Gandasi
Overview
Explore the profile of Nikhil R Gandasi including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
479
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Recent Articles
1.
Makam A, Sharma S, Nagle P, Sundaram N, Prasad V, Gandasi N
FASEB Bioadv
. 2025 Feb;
7(2):e1482.
PMID: 39917393
Pancreatic β-cells secrete insulin stored in large dense core vesicles (LDCV) by fusion of vesicle and plasma membrane during a process called insulin exocytosis. Insulin secretion is biphasic with a...
2.
Veerabhadraswamy P, Lata K, Dey S, Belekar P, Kothegala L, Prasad V, et al.
J Extracell Biol
. 2024 Dec;
3(11):e70014.
PMID: 39619685
Multivesicular bodies (MVBs) are vesicles of endosomal origin containing intraluminal vesicles, which upon fusion with plasma membrane, secrete exosomes. They play a significant role in the physiology and pathology of...
3.
Makam A, Dubey A, Maharana S, Gandasi N
Heliyon
. 2024 Oct;
10(19):e38307.
PMID: 39421365
Image processing and analysis are two significant areas that are highly important for interpreting enormous amounts of data obtained from microscopy-based experiments. Several image analysis tools exist for the general...
4.
Hill T, Gao R, Benrick A, Kothegala L, Rorsman N, Santos C, et al.
Nat Metab
. 2024 Sep;
6(11):2070-2081.
PMID: 39313541
Diabetes mellitus involves both insufficient insulin secretion and dysregulation of glucagon secretion. In healthy people, a fall in plasma glucose stimulates glucagon release and thereby increases counter-regulatory hepatic glucose production....
5.
Gandasi N, Rorsman P
Diabetologia
. 2024 Apr;
67(7):1446-1447.
PMID: 38578450
No abstract available.
6.
Paul S, Pallavi A, Gandasi N
Front Endocrinol (Lausanne)
. 2024 Mar;
15:1330058.
PMID: 38529398
Introduction: Pheophorbide A, a chlorophyll-breakdown product, is primarily investigated for its anti-oxidant and anti-inflammatory activity. Recent reports on pheophorbide A have shown its potential in lowering blood glucose levels, thus...
7.
Gandasi N, Gao R, Kothegala L, Pearce A, Santos C, Acreman S, et al.
Diabetologia
. 2023 Dec;
67(3):528-546.
PMID: 38127123
Aims/hypothesis: Diabetes mellitus is associated with impaired insulin secretion, often aggravated by oversecretion of glucagon. Therapeutic interventions should ideally correct both defects. Glucagon-like peptide 1 (GLP-1) has this capability but...
8.
Vaid R, Mendez A, Thombare K, Burgos-Panadero R, Robinot R, Fonseca B, et al.
Genome Res
. 2023 Mar;
33(3):299-313.
PMID: 36859333
Insights into host-virus interactions during SARS-CoV-2 infection are needed to understand COVID-19 pathogenesis and may help to guide the design of novel antiviral therapeutics. -Methyladenosine modification (mA), one of the...
9.
Kothegala L, Miranda C, Singh M, Krieger J, Gandasi N
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36834860
Recent developments suggest that increased glucagon and decreased somatostatin secretion from the pancreas contribute to hyperglycaemia in type-2 diabetes (T2D) patients. There is a huge need to understand changes in...
10.
Makam A, Biswas A, Kothegala L, Gandasi N
Biomedicines
. 2022 Nov;
10(11).
PMID: 36359215
Type-1-diabetes (T1D) is a multifactorial disorder with a global incidence of about 8.4 million individuals in 2021. It is primarily classified as an autoimmune disorder, where the pancreatic β-cells are...