Nigel Loveridge
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Explore the profile of Nigel Loveridge including associated specialties, affiliations and a list of published articles.
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24
Citations
1197
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Recent Articles
1.
Power J, Loveridge N, Kroger H, Parker M, Reeve J
Bone
. 2018 May;
114:81-89.
PMID: 29807138
Objectives: To quantitate differences between cases of hip fracture and controls in cortical width around the mid-femoral neck in men and women. Methods: Over 5 years, 64 (14 male) participants...
2.
Reeve J, Loveridge N
Bone
. 2014 Jan;
61:138-48.
PMID: 24412288
Every hip fracture begins with a microscopic crack, which enlarges explosively over microseconds. Most hip fractures in the elderly occur on falling from standing height, usually sideways or backwards. The...
3.
Gourion-Arsiquaud S, Lukashova L, Power J, Loveridge N, Reeve J, Boskey A
J Bone Miner Res
. 2012 Aug;
28(1):150-61.
PMID: 22865771
After the age of 60 years, hip fracture risk strongly increases, but only a fifth of this increase is attributable to reduced bone mineral density (BMD, measured clinically). Changes in...
4.
Prideaux M, Loveridge N, Pitsillides A, Farquharson C
PLoS One
. 2012 May;
7(5):e36786.
PMID: 22586496
Osteocytes are terminally differentiated osteoblasts which reside in a mineralized extracellular matrix (ECM). The factors that regulate this differentiation process are unknown. We have investigated whether ECM mineralization could promote...
5.
Power J, Doube M, van Bezooijen R, Loveridge N, Reeve J
Bone
. 2012 Feb;
50(5):1107-14.
PMID: 22353552
There is little information on the distribution of osteocytes within the individual cortical osteon, but using direct 3-D imaging in a single subject, Hannah et al. found a gradient with...
6.
van Lierop A, Hamdy N, Hamersma H, van Bezooijen R, Power J, Loveridge N, et al.
J Bone Miner Res
. 2011 Jul;
26(12):2804-11.
PMID: 21786318
Sclerosteosis is a rare bone sclerosing dysplasia, caused by loss-of-function mutations in the SOST gene, encoding sclerostin, a negative regulator of bone formation. The purpose of this study was to...
7.
Power J, Poole K, Van Bezooijen R, Doube M, Caballero-Alias A, Lowik C, et al.
J Bone Miner Res
. 2010 Mar;
25(8):1867-76.
PMID: 20200987
Remodeling imbalance in the elderly femoral neck can result in thin cortices and porosity predisposing to hip fracture. Hip osteoarthritis protects against intracapsular hip fracture. By secreting sclerostin, osteocytes may...
8.
Poole K, Mayhew P, Rose C, Brown J, Bearcroft P, Loveridge N, et al.
J Bone Miner Res
. 2009 Jul;
25(3):482-91.
PMID: 19594320
The anatomic distribution of cortical and cancellous bone in the femoral neck may be critical in determining resistance to fracture. We investigated the effects of aging on femoral neck bone...
9.
Thomas C, Mayhew P, Power J, Poole K, Loveridge N, Clement J, et al.
J Bone Miner Res
. 2009 May;
24(11):1808-18.
PMID: 19419312
Hip fracture risk rises 100- to 1000-fold over six decades of age, but only a minor part of this increase is explained by declining BMD. A potentially independent cause of...
10.
Rawlinson S, Murray D, Mosley J, Wright C, Bredl J, Saxon L, et al.
Bone
. 2009 May;
45(2):357-66.
PMID: 19409517
Bone strength is, in part, dependent on a mechanical input that regulates the (re)modelling of skeletal elements to an appropriate size and architecture to resist fracture during habitual use. The...