Nienke H van Teijlingen
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Explore the profile of Nienke H van Teijlingen including associated specialties, affiliations and a list of published articles.
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16
Citations
376
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Recent Articles
1.
van Teijlingen N, van Smoorenburg M, Sarrami-Forooshani R, Zijlstra-Willems E, van Hamme J, Borgdorff H, et al.
J Infect Dis
. 2024 Jul;
230(1):e43-e47.
PMID: 39052703
Dysbiosis of the vaginal microbiome poses a serious risk for sexual human immunodeficiency virus type 1 (HIV-1) transmission. Prevotella spp are abundant during vaginal dysbiosis and associated with enhanced HIV-1...
2.
van Teijlingen N, Eder J, Sarrami-Forooshani R, Zijlstra-Willems E, Roovers J, van Leeuwen E, et al.
Sci Rep
. 2023 Feb;
13(1):3283.
PMID: 36841916
Vaginal inflammation increases the risk for sexual HIV-1 transmission but underlying mechanisms remain unclear. In this study we assessed the impact of immune activation on HIV-1 susceptibility of primary human...
3.
van Teijlingen N, Helgers L, Sarrami-Forooshani R, Zijlstra-Willems E, van Hamme J, Segui-Perez C, et al.
EMBO J
. 2022 Aug;
41(19):e110629.
PMID: 35968812
Dysbiosis of vaginal microbiota is associated with increased HIV-1 acquisition, but the underlying cellular mechanisms remain unclear. Vaginal Langerhans cells (LCs) protect against mucosal HIV-1 infection via autophagy-mediated degradation of...
4.
Cloherty A, van Teijlingen N, Eisden T, van Hamme J, Rader A, Geijtenbeek T, et al.
Sci Rep
. 2021 Feb;
11(1):4767.
PMID: 33637808
Current direct-acting antiviral therapies are highly effective in suppressing HIV-1 replication. However, mucosal inflammation undermines prophylactic treatment efficacy, and HIV-1 persists in long-lived tissue-derived dendritic cells (DCs) and CD4 T...
5.
van Teijlingen N, Helgers L, Zijlstra-Willems E, van Hamme J, Ribeiro C, Strijbis K, et al.
J Reprod Immunol
. 2020 Feb;
138:103085.
PMID: 32004804
Dysbiosis of the vaginal microbiome as a result of overgrowth of anaerobic bacteria leads to bacterial vaginosis (BV) which is associated with increased inflammation in the genital mucosa. Moreover, BV...
6.
Hertoghs N, Nijmeijer B, van Teijlingen N, Fenton-May A, Kaptein T, van Hamme J, et al.
PLoS One
. 2019 Dec;
14(12):e0226651.
PMID: 31856198
A single HIV-1 variant establishes infection of the host after sexual contact. Identifying the phenotypic characteristics of these Transmitted Founder (T/F) viruses is important to understand the restriction mechanisms during...
7.
van Dalen R, De La Cruz Diaz J, Rumpret M, Fuchsberger F, van Teijlingen N, Hanske J, et al.
mBio
. 2019 May;
10(3).
PMID: 31088921
is a major cause of skin and soft tissue infections and aggravator of the inflammatory skin disease atopic dermatitis (AD [eczema]). Epicutaneous exposure to induces Th17 responses through skin Langerhans...
8.
Gringhuis S, Hertoghs N, Kaptein T, Zijlstra-Willems E, Sarrami-Fooroshani R, Sprokholt J, et al.
Nat Immunol
. 2017 Mar;
18(4):474.
PMID: 28323255
No abstract available.
9.
Gringhuis S, Hertoghs N, Kaptein T, Zijlstra-Willems E, Sarrami-Forooshani R, Sprokholt J, et al.
Nat Immunol
. 2016 Dec;
18(2):225-235.
PMID: 28024153
The mechanisms by which human immunodeficiency virus 1 (HIV-1) avoids immune surveillance by dendritic cells (DCs), and thereby prevents protective adaptive immune responses, remain poorly understood. Here we showed that...
10.
Probiotic Gut Microbiota Isolate Interacts with Dendritic Cells via Glycosylated Heterotrimeric Pili
Tytgat H, van Teijlingen N, Sullan R, Douillard F, Rasinkangas P, Messing M, et al.
PLoS One
. 2016 Mar;
11(3):e0151824.
PMID: 26985831
Mapping of the microbial molecules underlying microbiota-host interactions is key to understand how microbiota preserve mucosal homeostasis. A pivotal family of such bacterial molecules are pili. Pili are proteinaceous cell...