Niels C Danbolt
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Explore the profile of Niels C Danbolt including associated specialties, affiliations and a list of published articles.
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19
Citations
674
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Recent Articles
1.
Verbruggen L, Ates G, Lara O, De Munck J, Villers A, De Pauw L, et al.
Mol Psychiatry
. 2022 Feb;
27(4):2355-2368.
PMID: 35181756
The cystine/glutamate antiporter system x has been identified as the major source of extracellular glutamate in several brain regions as well as a modulator of neuroinflammation, and genetic deletion of...
2.
Farina M, Sandhu M, Parent M, Sanganahalli B, Derbin M, Dhaher R, et al.
Epilepsia
. 2021 Sep;
62(11):2858-2870.
PMID: 34536233
Objective: The astroglial enzyme glutamine synthetase (GS) is deficient in small loci in the brain in adult patients with different types of focal epilepsy; however, the role of this deficiency...
3.
Albertini G, Deneyer L, Ottestad-Hansen S, Zhou Y, Ates G, Walrave L, et al.
Glia
. 2018 Apr;
66(9):1845-1861.
PMID: 29693305
The communication between the immune and central nervous system (CNS) is affected in many neurological disorders. Peripheral injections of the endotoxin lipopolysaccharide (LPS) are widely used to study this communication:...
4.
Demuyser T, Deneyer L, Bentea E, Albertini G, Femenia T, Walrave L, et al.
World J Biol Psychiatry
. 2017 Sep;
20(5):381-392.
PMID: 28882088
The cystine/glutamate antiporter (system xc-) is believed to contribute to nonvesicular glutamate release from glial cells in various brain areas. Although recent investigations implicate system xc- in mood disorders, unambiguous...
5.
Li Y, Hessvik N, Danbolt N, Holen T
Microscopy (Oxf)
. 2016 Jul;
65(5):438-443.
PMID: 27460022
Little is known about olfactory glands' regulation despite their presumed importance for normal functioning of the cilia of olfactory neurons. The aim of this study was to establish an assay...
6.
Liefferinge J, Bentea E, Demuyser T, Albertini G, Follin-Arbelet V, Holmseth S, et al.
J Comp Neurol
. 2015 Oct;
524(5):1015-32.
PMID: 26494316
The cystine/glutamate antiporter or system Xc- exchanges cystine for glutamate, thereby supporting intracellular glutathione synthesis and nonvesicular glutamate release. The role of system Xc- in neurological disorders can be dual...
7.
Petr G, Sun Y, Frederick N, Zhou Y, Dhamne S, Hameed M, et al.
J Neurosci
. 2015 Apr;
35(13):5187-201.
PMID: 25834045
GLT-1 (EAAT2; slc1a2) is the major glutamate transporter in the brain, and is predominantly expressed in astrocytes, but at lower levels also in excitatory terminals. We generated a conditional GLT-1...
8.
Robel S, Buckingham S, Boni J, Campbell S, Danbolt N, Riedemann T, et al.
J Neurosci
. 2015 Feb;
35(8):3330-45.
PMID: 25716834
Epilepsy is one of the most common chronic neurologic diseases, yet approximately one-third of affected patients do not respond to anticonvulsive drugs that target neurons or neuronal circuits. Reactive astrocytes...
9.
Zhou Y, Wang X, Tzingounis A, Danbolt N, Larsson H
J Neurosci
. 2014 Oct;
34(40):13472-85.
PMID: 25274824
The EAAT2 glutamate transporter, accounts for >90% of hippocampal glutamate uptake. Although EAAT2 is predominantly expressed in astrocytes, ∼10% of EAAT2 molecules are found in axon terminals. Despite the lower...
10.
Yang M, Luna L, Sorbo J, Alseth I, Johansen R, Backe P, et al.
Free Radic Biol Med
. 2014 Sep;
77:41-8.
PMID: 25236744
The oxidation resistance gene 1 (OXR1) prevents oxidative stress-induced cell death by an unknown pathway. Here, depletion of human OXR1 (hOXR1) sensitized several human cell lines to hydrogen peroxide-induced oxidative...