Nidhi Nandu
Overview
Explore the profile of Nidhi Nandu including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
59
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Recent Articles
1.
Nandu N, Miller M, Tong Y, Lu Z
PLoS One
. 2024 Oct;
19(10):e0309541.
PMID: 39436873
Cost efficient and rapid detection tools to detect mutations especially those linked to drug-resistance are important to address concerns of the rising multi-drug resistance infections. Here we integrated dual probes,...
2.
Kachwala M, Smith C, Nandu N, Yigit M
Nanoscale
. 2022 Sep;
14(37):13500-13504.
PMID: 36102688
We have developed a 'recombinase amplified CRISPR enhanced chain reaction' (RACECAR) assay that can detect as little as 40 copies of hepatitis B virus (HBV) genome using a benchtop spectrofluorometer....
3.
Smith C, Hizir M, Nandu N, Yigit M
Anal Chem
. 2021 Dec;
94(2):1195-1202.
PMID: 34964601
Here, we report a biomarker-free detection of various biological targets through a programmed machine learning algorithm and an automated computational selection process termed algorithmically guided optical nanosensor selector (AGONS). The...
4.
Smith C, Kachwala M, Nandu N, Yigit M
ACS Synth Biol
. 2021 Jun;
10(7):1785-1791.
PMID: 34142793
CRISPR-Cas12a is a powerful platform for DNA-based diagnostics. The detection scheme relies on unselective shredding of a fluorescent ssDNA reporter upon target DNA recognition. To extend the reporter library beyond...
5.
Nandu N, Smith C, Uyar T, Chen Y, Kachwala M, He M, et al.
ACS Appl Nano Mater
. 2021 Jun;
3(12):11709-11714.
PMID: 34095773
A two-dimensional nanoparticle-single-stranded DNA (ssDNA) array has been assembled for the detection of bacterial species using machine-learning (ML) algorithms. Out of 60 unknowns prepared from bacterial lysates, 54 unknowns were...
6.
Kachwala M, Smith C, Nandu N, Yigit M
Anal Chem
. 2021 Jan;
93(4):1934-1938.
PMID: 33404234
Hybridization chain reaction (HCR) is a DNA-based target-induced cascade reaction. Due to its unique enzyme-free amplification feature, HCR is often employed for sensing applications. Much like DNA nanostructures that have...
7.
Nandu N, Smith C, Kachwala M, Yigit M
Chembiochem
. 2020 Oct;
22(4):662-665.
PMID: 33022809
Two dimensional nanoparticles (2D-NPs) along with other nanoscale materials have been deemed to be the next generation of artificial enzymes (nanozymes). The low-cost bulk-scale production, ease of storage and modification...
8.
He M, Nandu N, Uyar T, Royzen M, Yigit M
Chem Commun (Camb)
. 2020 Jun;
56(53):7313-7316.
PMID: 32478344
Hydrogels are networks of polymers that can be used for packaging different payload types. They are proven to be versatile materials for various biomedical applications. Implanted hydrogels with encapsulated drugs...
9.
Smith C, Nandu N, Kachwala M, Chen Y, Uyar T, Yigit M
Biochemistry
. 2020 Apr;
59(15):1474-1481.
PMID: 32233423
The CRISPR-Cas12a nuclease shreds short single-stranded DNA (ssDNA) substrates indiscriminately through trans-cleavage upon activation with a specific target DNA. This shredding activity offered the potential for development of ssDNA-templated probes...
10.
Nandu N, Hizir M, Roberston N, Ozturk B, Yigit M
Chembiochem
. 2018 Sep;
20(14):1861-1867.
PMID: 30198177
Two-dimensional MoS nanoparticles (2D-nps) exhibit artificial enzyme properties that can be regulated at bio-nanointerfaces. We discovered that protein lipase is able to tune the peroxidase-like activity of MoS 2D-nps, offering...