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Nicoletta Labarile

Explore the profile of Nicoletta Labarile including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Valentini A, Arborea G, Grassi I, Savino M, Labarile N, Donghia R, et al.
Oncol Lett . 2025 Jan; 29(3):140. PMID: 39850722
Pancreatic ductal adenocarcinoma (PDA) is a highly aggressive tumor with limited treatment options. Zolbetuximab, a monoclonal antibody against the tight junction protein Claudin 18.2 has recently been developed. At present,...
2.
Piccinno E, Scalavino V, Labarile N, Armentano R, Giannelli G, Serino G
Pharmaceutics . 2025 Jan; 16(12. PMID: 39771533
Background/objectives: KRT23 was recently discovered as an epithelial-specific intermediate filament protein in the type I keratin family. Many studies have underlined keratin's involvement in several biological processes as well as...
3.
Scalavino V, Piccinno E, Labarile N, Armentano R, Giannelli G, Serino G
Int J Mol Sci . 2024 Aug; 25(15). PMID: 39126032
Cyclic nucleotide phosphodiesterases (PDEs) consist of a family of enzymes expressed in several types of cells, including inflammatory cells, that play a pivotal role in inflammation. Several studies have demonstrated...
4.
Piccinno E, Scalavino V, Labarile N, De Marinis L, Armentano R, Giannelli G, et al.
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38892168
Pinin (PNN) is a desmosome-associated protein that reinforces the organization of keratin intermediate filaments and stabilizes the anchoring of the cytoskeleton network to the lateral surface of the plasma membrane....
5.
Sanese P, De Marco K, Lepore Signorile M, La Rocca F, Forte G, Latrofa M, et al.
J Exp Clin Cancer Res . 2024 May; 43(1):151. PMID: 38812026
Background: SMYD3 has been found implicated in cancer progression. Its overexpression correlates with cancer growth and invasion, especially in gastrointestinal tumors. SMYD3 transactivates multiple oncogenic mechanisms, favoring cancer development. Moreover,...
6.
Piccinno E, Scalavino V, Labarile N, Bianco G, Savino M, Armentano R, et al.
Int J Mol Sci . 2024 Jan; 25(1). PMID: 38203664
Desmosomes are essential structures for ensuring tissue functions, and their deregulation is involved in the development of colorectal cancer (CRC). JUP (γ-catenin) is a desmosome adhesion component that also acts...