Nicoletta Casartelli
Overview
Explore the profile of Nicoletta Casartelli including associated specialties, affiliations and a list of published articles.
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40
Citations
2921
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Recent Articles
1.
Bolland W, Marechal I, Petiot C, Porrot F, Guivel-Benhassine F, Brelot A, et al.
J Virol
. 2024 Nov;
99(1):e0182324.
PMID: 39570043
Membrane fusion occurs at the early stages of SARS-CoV-2 replication, during entry of the virus, and later during the formation of multinucleated cells called syncytia. Fusion is mediated by the...
2.
Serrano T, Casartelli N, Ghasemi F, Wioland H, Cuvelier F, Salles A, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(48):e2407835121.
PMID: 39556735
Many enveloped viruses bud from the plasma membrane that is tightly associated with a dense and thick actin cortex. This actin network represents a significant challenge for membrane deformation and...
3.
Dufloo J, Planchais C, Fremont S, Lorin V, Guivel-Benhassine F, Stefic K, et al.
Nat Commun
. 2022 Feb;
13(1):630.
PMID: 35110562
Broadly neutralizing antibodies (bNAbs) targeting the HIV-1 envelope glycoprotein (Env) are promising molecules for therapeutic or prophylactic interventions. Beyond neutralization, bNAbs exert Fc-dependent functions including antibody-dependent cellular cytotoxicity and activation...
4.
Martinat C, Cormier A, Tobaly-Tapiero J, Palmic N, Casartelli N, Mahboubi B, et al.
Nat Commun
. 2021 Jul;
12(1):4582.
PMID: 34321470
SAMHD1 is a cellular triphosphohydrolase (dNTPase) proposed to inhibit HIV-1 reverse transcription in non-cycling immune cells by limiting the supply of the dNTP substrates. Yet, phosphorylation of T592 downregulates SAMHD1...
5.
Buchrieser J, Dufloo J, Hubert M, Monel B, Planas D, Rajah M, et al.
EMBO J
. 2021 Feb;
40(3):e107405.
PMID: 33522642
No abstract available.
6.
Buchrieser J, Dufloo J, Hubert M, Monel B, Planas D, Rajah M, et al.
EMBO J
. 2020 Oct;
39(23):e106267.
PMID: 33051876
Severe cases of COVID-19 are associated with extensive lung damage and the presence of infected multinucleated syncytial pneumocytes. The viral and cellular mechanisms regulating the formation of these syncytia are...
7.
Staropoli I, Dufloo J, Ducher A, Commere P, Sartori-Rupp A, Novault S, et al.
J Virol
. 2019 Dec;
94(6).
PMID: 31852789
The HIV-1 Env protein is exposed at the surface of virions and infected cells. Env fluctuates between different closed and open structural states and these conformations influence both viral infectivity...
8.
Passos V, Zillinger T, Casartelli N, Wachs A, Xu S, Malassa A, et al.
J Virol
. 2019 Oct;
93(24).
PMID: 31597782
When expressed in virus-producing cells, the cellular multipass transmembrane protein SERINC5 reduces the infectivity of HIV-1 particles and is counteracted by HIV-1 Nef. Due to the unavailability of an antibody...
9.
Chauveau L, Donahue D, Monel B, Porrot F, Bruel T, Richard L, et al.
J Virol
. 2017 Aug;
91(21).
PMID: 28814521
HIV-1 poorly infects monocyte-derived dendritic cells (MDDCs). This is in large part due to SAMHD1, which restricts viral reverse transcription. Pseudotyping HIV-1 with vesicular stomatitis virus G protein (VSV-G) strongly...
10.
Monel B, Compton A, Bruel T, Amraoui S, Burlaud-Gaillard J, Roy N, et al.
EMBO J
. 2017 May;
36(12):1653-1668.
PMID: 28473450
The cytopathic effects of Zika virus (ZIKV) are poorly characterized. Innate immunity controls ZIKV infection and disease in most infected patients through mechanisms that remain to be understood. Here, we...