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Nicole Poweleit

Explore the profile of Nicole Poweleit including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 267
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Recent Articles
1.
Catalano C, Lucier K, To D, Senko S, Tran N, Farwell A, et al.
J Struct Biol . 2024 Jun; 216(3):108105. PMID: 38852682
Human serum albumin (HSA) is the most prevalent plasma protein in the human body, accounting for 60 % of the total plasma protein. HSA plays a major pharmacokinetic function, serving...
2.
Tran N, Senko S, Lucier K, Farwell A, Silva S, Dip P, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38674110
Membrane proteins constitute about 20% of the human proteome and play crucial roles in cellular functions. However, a complete understanding of their structure and function is limited by their hydrophobic...
3.
Bruhn J, Scapin G, Cheng A, Mercado B, Waterman D, Ganesh T, et al.
Front Mol Biosci . 2021 Jul; 8:648603. PMID: 34327213
The emerging field of microcrystal electron diffraction (MicroED) is of great interest to industrial researchers working in the drug discovery and drug development space. The promise of being able to...
4.
Rumachik N, Malaker S, Poweleit N, Maynard L, Adams C, Leib R, et al.
Mol Ther Methods Clin Dev . 2020 Sep; 18:98-118. PMID: 32995354
Different approaches are used in the production of recombinant adeno-associated virus (rAAV). The two leading approaches are transiently transfected human HEK293 cells and live baculovirus infection of () insect cells....
5.
Dickinson M, Myasnikov A, Eriksen J, Poweleit N, Stroud R
Proc Natl Acad Sci U S A . 2020 Jan; 117(4):1988-1993. PMID: 31924746
Voltage-gated ion channels endow membranes with excitability and the means to propagate action potentials that form the basis of all neuronal signaling. We determined the structure of a voltage-gated sodium...
6.
Poweleit N, Czudnochowski N, Nakagawa R, Trinidad D, Murphy K, Sassetti C, et al.
Elife . 2019 Dec; 8. PMID: 31886769
The ESX (or Type VII) secretion systems are protein export systems in mycobacteria and many Gram-positive bacteria that mediate a broad range of functions including virulence, conjugation, and metabolic regulation....
7.
Poweleit N, Ge P, Nguyen H, Ogorzalek Loo R, Gunsalus R, Zhou Z
Nat Microbiol . 2016 Dec; 2:16264. PMID: 28004660
No abstract available.
8.
Poweleit N, Ge P, Nguyen H, Ogorzalek Loo R, Gunsalus R, Zhou Z
Nat Microbiol . 2016 Dec; 2:16222. PMID: 27922015
Archaea use flagella known as archaella-distinct both in protein composition and structure from bacterial flagella-to drive cell motility, but the structural basis of this function is unknown. Here, we report...
9.
Gunsalus R, Cook L, Crable B, Rohlin L, McDonald E, Mouttaki H, et al.
Stand Genomic Sci . 2016 Jan; 11:2. PMID: 26744606
Methanospirillum hungatei strain JF1 (DSM 864) is a methane-producing archaeon and is the type species of the genus Methanospirillum, which belongs to the family Methanospirillaceae within the order Methanomicrobiales. Its...
10.
Bor B, Poweleit N, Bois J, Cen L, Bedree J, Zhou Z, et al.
Microb Ecol . 2015 Nov; 71(1):243-55. PMID: 26597961
Despite many examples of obligate epibiotic symbiosis (one organism living on the surface of another) in nature, such an interaction has rarely been observed between two bacteria. Here, we further...