Nicole M Zaleski
Overview
Explore the profile of Nicole M Zaleski including associated specialties, affiliations and a list of published articles.
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8
Citations
80
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Recent Articles
1.
Challa A, Zaleski N, Jerome R, Lavieri R, Shirey-Rice J, Barnado A, et al.
Front Genet
. 2021 Aug;
12:707836.
PMID: 34394194
Repurposing is an increasingly attractive method within the field of drug development for its efficiency at identifying new therapeutic opportunities among approved drugs at greatly reduced cost and time of...
2.
Challa A, Lavieri R, Lewis J, Zaleski N, Shirey-Rice J, Harris P, et al.
Assay Drug Dev Technol
. 2019 Nov;
17(8):352-363.
PMID: 31769998
Drug repurposing is the application of approved drugs to treat diseases separate and distinct from their original indications. Herein, we define the scope of all practical precision drug repurposing using...
3.
Pulley J, Rhoads J, Jerome R, Challa A, Erreger K, Joly M, et al.
Annu Rev Pharmacol Toxicol
. 2019 Jul;
60:333-352.
PMID: 31337270
The promise of drug repurposing is to accelerate the translation of knowledge to treatment of human disease, bypassing common challenges associated with drug development to be more time- and cost-efficient....
4.
Linder J, Batey K, Johnston R, Cohen E, Wang Y, Wang X, et al.
J Reprod Biotechnol Fertil
. 2019 Jan;
7:14-27.
PMID: 30637122
Background: The Vanderbilt Institute for Clinical and Translational Research piloted the development of Project PLACENTA (PathLink Acquired gEstatioNal Tissue bAnk). This project investigated the feasibility of a fresh gestational tissue...
5.
Pulley J, Jerome R, Shirey-Rice J, Zaleski N, Naylor H, Pruijssers A, et al.
Future Med Chem
. 2018 May;
10(12):1395-1398.
PMID: 29788759
No abstract available.
6.
Pulley J, Jerome R, Ogletree M, Bernard G, Lavieri R, Zaleski N, et al.
Target Oncol
. 2017 Dec;
13(1):61-68.
PMID: 29218624
Metastatic cancers impose significant burdens on patients, affecting quality of life, morbidity, and mortality. Even during remission, microscopic metastases can lurk, but few therapies directly target tumor cell metastasis. Agents...
7.
Pulley J, Jerome R, Zaleski N, Shirey-Rice J, Pruijssers A, Lavieri R, et al.
Assay Drug Dev Technol
. 2017 Dec;
15(8):354-361.
PMID: 29193979
Many animal models of disease are suboptimal in their representation of human diseases and lack of predictive power in the success of pivotal human trials. In the context of repurposing...
8.
Pulley J, Shirey-Rice J, Lavieri R, Jerome R, Zaleski N, Aronoff D, et al.
Assay Drug Dev Technol
. 2017 Apr;
15(3):113-119.
PMID: 28379727
The potential impact of using human genetic data linked to longitudinal electronic medical records on drug development is extraordinary; however, the practical application of these data necessitates some organizational innovations....