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Nicole Janssen

Explore the profile of Nicole Janssen including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 47
Citations 1135
Followers 0
Related Specialties
Environmental Health
Oncology
Toxicology
Top 10 Co-Authors
Gerard Hoek
Graham Pawelec
Bert Brunekreef
Danielle Vienneau
Jie Chen
Massimo Stafoggia
Klea Katsouyanni
Maciej Strak
Kees de Hoogh
Mariska Bauwelinck
Published In
Environ Res
Environ Int
Sci Total Environ
Hum Mutat
J Immunother Cancer
Affiliations
Soon will be listed here.
Recent Articles
1.
First-in-class ultralong-target-residence-time p38α inhibitors as a mitosis-targeted therapy for colorectal cancer
Rudalska R, Harbig J, Forster M, Woelffing P, Esposito A, Kudolo M, et al.
Nat Cancer . 2025 Jan; 6(2):259-277. PMID: 39820127
Colorectal cancer (CRC) constitutes the second leading cause of cancer-related death worldwide and advanced CRCs are resistant to targeted therapies, chemotherapies and immunotherapies. p38α (Mapk14) has been suggested as a...
2.
Long-term exposure to ambient air pollution and risk of lung cancer - A comparative analysis of incidence and mortality in four administrative cohorts in the ELAPSE study
Chen J, Atkinson R, Andersen Z, Oftedal B, Stafoggia M, Lim Y, et al.
Environ Res . 2024 Oct; 263(Pt 3):120236. PMID: 39455045
Background: Studies have linked air pollution to lung cancer incidence and mortality, but few have compared these associations, which may differ due to cancer survival variations. We aimed to evaluate...
3.
Air pollution exposure and mortality from neurodegenerative diseases in the Netherlands: A population-based cohort study
Peters S, Bouma F, Hoek G, Janssen N, Vermeulen R
Environ Res . 2024 Jul; 259:119552. PMID: 38964584
Background: Long-term exposure to ambient air pollution has been linked with all-cause mortality and cardiovascular and respiratory diseases. Suggestive associations between ambient air pollutants and neurodegeneration have also been reported,...
4.
Putative Cancer Stem Cell Markers are Frequently Expressed by Melanoma Cells and but are also Present in Benign Differentiated Cells
Speigl L, Janssen N, Weide B, Sinnberg T, Pawelec G, Shipp C
Front Biosci (Landmark Ed) . 2023 Oct; 28(9):193. PMID: 37796710
Background: Currently, there remains an incomplete view of cancer stem cells (CSCs) in solid tumours. Methods: We studied a panel of putative CSC surface markers (ALDH1A1, ABCG2, CD44v7/8, CD44v10, CD133,...
5.
Protocol for establishing a coculture with fibroblasts and colorectal cancer organoids
Wallisch S, Neef S, Denzinger L, Monch D, Koch J, Marzi J, et al.
STAR Protoc . 2023 Aug; 4(3):102481. PMID: 37542715
The tumor microenvironment is essential for mediating drug resistance and tumor progression. Here, we present a coculture system, which enables drug testing of colorectal cancer organoids and fibroblasts without additional...
6.
Exploring associations between residential exposure to pesticides and birth outcomes using the Dutch birth registry
Simoes M, Vermeulen R, Portengen L, Janssen N, Huss A
Environ Int . 2023 Jul; 178:108085. PMID: 37421898
Background: Maternal occupational exposure to pesticides has been linked to adverse birth outcomes but associations with residential pesticide exposures are inconclusive. Objectives: To explore associations between residential exposure to specific...
7.
Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PM, BC, NO, and O: An Analysis of European Cohorts in the ELAPSE Project
Brunekreef B, Strak M, Chen J, Andersen Z, Atkinson R, Bauwelinck M, et al.
Res Rep Health Eff Inst . 2022 Sep; (208):1-127. PMID: 36106702
Introduction: Epidemiological cohort studies have consistently found associations between long-term exposure to outdoor air pollution and a range of morbidity and mortality endpoints. Recent evaluations by the World Health Organization...
8.
Triple Targeting of HER Receptors Overcomes Heregulin-mediated Resistance to EGFR Blockade in Colorectal Cancer
Rau A, Janssen N, Kuhl L, Sell T, Kalmykova S, Murdter T, et al.
Mol Cancer Ther . 2022 Mar; 21(5):799-809. PMID: 35247930
Current treatment options for patients with advanced colorectal cancers include anti-EGFR/HER1 therapy with the blocking antibody cetuximab. Although a subset of patients with KRAS WT disease initially respond to the...
9.
Residential proximity to livestock animals and mortality from respiratory diseases in The Netherlands: A prospective census-based cohort study
Simoes M, Janssen N, Heederik D, Smit L, Vermeulen R, Huss A
Environ Int . 2022 Feb; 161:107140. PMID: 35189407
Background: There is increasing evidence of associations between residential proximity to livestock farms and respiratory morbidity, but less is known about potential effects on respiratory mortality among residents. Objectives: We...
10.
Residential proximity to crops and agricultural pesticide use and cause-specific mortality: A prospective census-based cohort study in the Netherlands
Simoes M, Huss A, Brouwer M, Krop E, Janssen N, Vermeulen R
Sci Total Environ . 2022 Jan; 817:152932. PMID: 35007583
Background: There is continued concern about residential proximity to agricultural pesticide use and possible adverse health effects. Studies on this subject have been scarce with inconsistent results. We explored associations...