Nicole E Smalley
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Explore the profile of Nicole E Smalley including associated specialties, affiliations and a list of published articles.
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19
Citations
510
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Recent Articles
1.
Banerjee S, Smalley N, Saenjamsai P, Fehr A, Dandekar A, Cabeen M, et al.
bioRxiv
. 2025 Feb;
PMID: 39975224
In the opportunistic pathogen , the nitrogen-related phosphotransferase system (PTS) influences multiple virulence behaviors. The PTS is comprised of three enzymes: first PtsP, then the PtsO phosphocarrier, and the final...
2.
Cruz R, Freeman T, Asfahl K, Smalley N, Dandekar A
J Bacteriol
. 2024 Dec;
207(1):e0034424.
PMID: 39670758
uses quorum sensing (QS) to regulate the expression of dozens of genes, many of which encode shared products, called "public goods." possesses two complete acyl-homoserine lactone (AHL) QS circuits: the...
3.
Soto-Aceves M, Smalley N, Schaefer A, Greenberg E
J Bacteriol
. 2024 Dec;
207(1):e0047524.
PMID: 39660889
No abstract available.
4.
Soto-Aceves M, Smalley N, Schaefer A, Greenberg E
J Bacteriol
. 2024 Sep;
206(10):e0013824.
PMID: 39235221
The opportunistic pathogen has complex quorum sensing (QS) circuitry, which involves two acylhomoserine lactone (AHL) systems, the LasI AHL synthase and LasR AHL-dependent transcriptional activator system and the RhlI AHL...
5.
Soto-Aceves M, Smalley N, Schaefer A, Greenberg E
bioRxiv
. 2024 Apr;
PMID: 38562759
The opportunistic pathogen has complex quorum sensing (QS) circuitry, which involves two acylhomoserine lactone (AHL) systems, the LasI AHL synthase and LasR AHL-dependent transcriptional activator system and the RhlI AHL...
6.
Kostylev M, Smalley N, Chao M, Greenberg E
J Bacteriol
. 2023 Nov;
205(12):e0022623.
PMID: 38032211
is an opportunistic bacterial pathogen. Many of its virulence genes are regulated by quorum sensing (QS), a form of cell-to-cell communication. QS consists of three interlinked circuits, LasI-R, Rhl-R, and...
7.
Asfahl K, Smalley N, Chang A, Dandekar A
mSystems
. 2022 Apr;
7(2):e0011322.
PMID: 35471121
In people with the genetic disease cystic fibrosis (CF), bacterial infections involving the opportunistic pathogen Pseudomonas aeruginosa are a significant cause of morbidity and mortality. P. aeruginosa uses a cell-cell...
8.
Smalley N, Schaefer A, Asfahl K, Perez C, Greenberg E, Dandekar A
mBio
. 2022 Mar;
13(1):e0016122.
PMID: 35294222
In the opportunistic pathogenic bacterium Pseudomonas aeruginosa acyl-homoserine lactone quorum sensing (QS) can activate expression of dozens to hundreds of genes depending on the strain under investigation. Many QS-activated genes...
9.
Abisado R, Kimbrough J, Mckee B, Craddock V, Smalley N, Dandekar A, et al.
Appl Environ Microbiol
. 2021 Apr;
87(12):e0002921.
PMID: 33837019
The Pseudomonas aeruginosa LasR-LasI (LasR-I) quorum sensing system regulates secreted proteases that can be exploited by cheaters, such as quorum sensing receptor-defective () mutants. mutants emerge in populations growing on...
10.
Klaus J, Majerczyk C, Moon S, Eppler N, Smith S, Tuma E, et al.
Appl Environ Microbiol
. 2020 Oct;
86(24).
PMID: 33008823
The bacterium produces an arsenal of secondary metabolites that have diverse structures and roles in the ecology of this soil-dwelling bacterium. In coculture experiments, strain E264 secretes an antimicrobial that...