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Nicole Diedrichs

Explore the profile of Nicole Diedrichs including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 75
Followers 0
Related Specialties
Chemistry
Biochemistry
Pharmacology
Top 10 Co-Authors
Ning Zou
K C Nicolaou
Federico Bernal
Petri M Pihko
Katja Zimmermann
Barbara Albrecht-Kupper
Noriaki Uesaka
Walter Hubsch
Jacques P Ragot
Wenyuan Qian
Published In
Angew Chem Int Ed Engl
Circ Heart Fail
Org Lett
ChemMedChem
J Am Chem Soc
Affiliations
Soon will be listed here.
Recent Articles
1.
Neladenoson Bialanate Hydrochloride: A Prodrug of a Partial Adenosine A Receptor Agonist for the Chronic Treatment of Heart Diseases
Meibom D, Albrecht-Kupper B, Diedrichs N, Hubsch W, Kast R, Kramer T, et al.
ChemMedChem . 2017 May; 12(10):728-737. PMID: 28488817
Adenosine is known to be released under a variety of physiological and pathophysiological conditions to facilitate the protection and regeneration of injured ischemic tissues. The activation of myocardial adenosine A...
2.
Chronic therapy with a partial adenosine A1-receptor agonist improves left ventricular function and remodeling in dogs with advanced heart failure
Sabbah H, Gupta R, Kohli S, Wang M, Rastogi S, Zhang K, et al.
Circ Heart Fail . 2013 Apr; 6(3):563-71. PMID: 23564604
Background: Adenosine elicits cardioprotection through A1-receptor activation. Therapy with adenosine A1-receptor agonists, however, is limited by undesirable actions of full agonism, such as bradycardia. This study examined the effects of...
3.
Total synthesis and structural elucidation of azaspiracid-1. Construction of key building blocks for originally proposed structure
Nicolaou K, Pihko P, Bernal F, Frederick M, Qian W, Uesaka N, et al.
J Am Chem Soc . 2006 Feb; 128(7):2244-57. PMID: 16478178
Syntheses of the three key building blocks (65, 98, and 100) required for the total synthesis of the proposed structure of azaspiracid-1 (1a) are described. Key steps include a TMSOTf-induced...
4.
Stereoselective synthesis of (+/-)-rocaglaol analogues
Thede K, Diedrichs N, Ragot J
Org Lett . 2004 Nov; 6(24):4595-7. PMID: 15548084
An intramolecular hydroxy epoxide opening was used to access the cyclopenta[b]benzofuran ring system of the natural product rocaglaol (2). Our route allowed the stereocontrolled preparation of the rocaglaol derivative (+/-)-(1S*,3S*,3aR*,8bS*)-3b....
5.
Synthesis of the FGHI Ring System of Azaspiracid We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical...
Nicolaou K, Pihko P, Diedrichs N, Zou N, Bernal F
Angew Chem Int Ed Engl . 2001 May; 40(9):1573. PMID: 11353466
No abstract available.
6.
Synthesis of the FGHI Ring System of Azaspiracid We thank Dr. D. H. Huang and Dr. G. Siuzdak for NMR spectroscopic and mass spectrometric assistance, respectively. Financial support for this work was provided by The Skaggs Institute for Chemical...
Nicolaou K, Pihko P, Diedrichs N, Zou N, Bernal F
Angew Chem Int Ed Engl . 2001 Apr; 40(7):1262-1265. PMID: 11301444
No abstract available.