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Nicolas Verhoeven

Explore the profile of Nicolas Verhoeven including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 30
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Recent Articles
1.
Verhoeven N, Oshima Y, Cartier E, Bippes C, Neutzner A, Boyman L, et al.
Dev Cell . 2024 Oct; 60(1):40-50.e5. PMID: 39423819
We report that the outer mitochondrial membrane (OMM)-associated E3 Ub ligase MARCH5 is vital for generating mitochondria-derived pre-peroxisomes. In human immortalized cells, MARCH5 knockout leads to the accumulation of immature...
2.
Verhoeven N, Oshima Y, Cartier E, Neutzner A, Boyman L, Karbowski M
bioRxiv . 2023 Sep; PMID: 37693581
Summary: The authors found that mitochondrial E3 Ub ligase MARCH5 controls the formation of mitochondria-derived pre-peroxisomes. The data support the hybrid, mitochondria-dependent model of peroxisome biogenesis and reveal that MARCH5...
3.
Karbowski M, Boyman L, Garber L, Joca H, Verhoeven N, Coleman A, et al.
bioRxiv . 2023 Sep; PMID: 37693446
Background: The intracellular Na concentration ([Na ] ) is a crucial but understudied regulator of cardiac myocyte function. The Na /K ATPase (NKA) controls the steady-state [Na ] and thereby...
4.
Greiser M, Karbowski M, Kaplan A, Coleman A, Verhoeven N, Mannella C, et al.
Elife . 2023 Jun; 12. PMID: 37272417
Mitochondrial ATP production in ventricular cardiomyocytes must be continually adjusted to rapidly replenish the ATP consumed by the working heart. Two systems are known to be critical in this regulation:...
5.
Karbowski M, Oshima Y, Verhoeven N
Cell Mol Life Sci . 2022 Oct; 79(11):574. PMID: 36308570
Through their role in energy generation and regulation of several vital pathways, including apoptosis and inflammation, mitochondria are critical for the life of eukaryotic organisms. Mitochondrial dysfunction is a major...
6.
Oshima Y, Verhoeven N, Cartier E, Karbowski M
Autophagy . 2021 Sep; 17(11):3884-3886. PMID: 34486484
Among other mechanisms, mitochondrial membrane dynamics including mitochondrial fission and fusion, and the activity of the ubiquitin (Ub)-proteasome system (UPS) both are critical for maintaining mitochondrial function. To advance our...
7.
Oshima Y, Cartier E, Boyman L, Verhoeven N, Polster B, Huang W, et al.
J Cell Biol . 2021 Apr; 220(6). PMID: 33851959
Here, we report that acute reduction in mitochondrial translation fidelity (MTF) causes ubiquitination of the inner mitochondrial membrane (IMM) proteins, including TRAP1 and CPOX, which occurs selectively in mitochondria with...
8.
Verhoeven N, Neoh T, Ohashi T, Furuta T, Kurozumi S, Yoshii H
Carbohydr Res . 2012 Feb; 351:74-80. PMID: 22341504
β-Maltose monohydrate was transformed into an anhydrous form by ethanol-mediated method under several temperatures with agitation. A new stable anhydrous form of β-maltose (Mβ(s)) was obtained, as substantiated by the...