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Nicolas Charles

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Articles 64
Citations 1567
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Recent Articles
1.
Robert M, Villain E, Yatim N, Mageau A, Charles N, Culina S, et al.
Eur Respir J . 2025 Jan; 65(1). PMID: 39746766
No abstract available.
2.
Simon Q, Tchen J, Charles N
Med Sci (Paris) . 2024 Dec; 40(11):815-818. PMID: 39656976
No abstract available.
3.
Himbert M, Jourde-Chiche N, Chapart L, Charles N, Baumstarck K, Daugas E
RMD Open . 2024 Jun; 10(2). PMID: 38942591
Objectives: Discontinuation or continuation of maintenance immunosuppressive therapy (MIST) after a severe lupus nephritis (LN) requires measuring the risk of relapse but reliable clinical and biological markers are lacking. The...
4.
Tchen J, Simon Q, Chapart L, Thaminy M, Vibhushan S, Saveanu L, et al.
Nat Commun . 2024 Apr; 15(1):3389. PMID: 38649353
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by anti-nuclear autoantibodies whose production is promoted by autoreactive T follicular helper (TFH) cells. During SLE pathogenesis, basophils accumulate in secondary...
5.
Kolkhir P, Altrichter S, Badloe F, Belasri H, Charles N, De Vriese S, et al.
Nat Med . 2024 Mar; 30(4):920-922. PMID: 38429523
No abstract available.
6.
Charles N, Kortekaas-Krohn I, Kocaturk E, Scheffel J, Altrichter S, Steinert C, et al.
Allergy . 2023 Aug; 78(12):3118-3135. PMID: 37555488
Autoimmunity is the break of tolerance to self-antigens that leads to organ-specific or systemic diseases often characterized by the presence of pathogenic autoreactive antibodies (AAb) produced by plasmablast and/or plasma...
7.
Gaillard F, Bachelet D, Couchoud C, Laouenan C, Peoch K, Simon Q, et al.
Rheumatology (Oxford) . 2023 Jun; 63(3):780-786. PMID: 37338593
Objectives: Lupus activity has long been considered to decline after initiation of maintenance dialysis (MD). This assumption is based on limited historical data. We aimed to describe the natural history...
8.
Mageau A, Tchen J, Ferre V, Nicaise-Roland P, Descamps D, Delory N, et al.
J Autoimmun . 2022 Dec; 134:102987. PMID: 36563528
Objective: To evaluate the specific response of SLE patients to BNT162b2 vaccination and its impact on autoimmunity defined as in vivo production of interferon-alpha (IFNα) by plasmacytoid dendritic cells (pDCs)...
9.
Tchen J, Simon Q, Chapart L, Pellefigues C, Karasuyama H, Miyake K, et al.
Front Immunol . 2022 Jul; 13:900532. PMID: 35844602
Tissue-specific mouse models are essential tools to decipher the role of each cell compartment and/or their expressed genes in the pathophysiology of diseases. Here, we describe a new knock-in mouse...
10.
Tchen J, Charles N
Med Sci (Paris) . 2022 Apr; 38(4):366-373. PMID: 35485897
Understanding the pathophysiology of antibody-driven autoimmune diseases (AAID) represents a major challenge for the biomedical community to develop innovative therapeutic strategies that are still lacking to control these diseases. If...