Nicolae Sapoval
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Explore the profile of Nicolae Sapoval including associated specialties, affiliations and a list of published articles.
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22
Citations
459
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Recent Articles
1.
Wang M, Lou E, Sapoval N, Kim E, Kalvapalle P, Kille B, et al.
Nat Commun
. 2024 Jul;
15(1):6306.
PMID: 39060254
Tiled amplicon sequencing has served as an essential tool for tracking the spread and evolution of pathogens. Over 15 million complete SARS-CoV-2 genomes are now publicly available, most sequenced and...
2.
Sapoval N, Liu Y, Curry K, Kille B, Huang W, Kokroko N, et al.
bioRxiv
. 2024 Jun;
PMID: 38895276
The advent of long-read sequencing of microbiomes necessitates the development of new taxonomic profilers tailored to long-read shotgun metagenomic datasets. Here, we introduce Lemur and Magnet, a pair of tools...
3.
Liu Y, Sapoval N, Gallego-Garcia P, Tomas L, Posada D, Treangen T, et al.
Nat Commun
. 2024 May;
15(1):4545.
PMID: 38806450
Wastewater surveillance for SARS-CoV-2 provides early warnings of emerging variants of concerns and can be used to screen for novel cryptic linked-read mutations, which are co-occurring single nucleotide mutations that...
4.
Sapoval N, Tanevski M, Treangen T
Pac Symp Biocomput
. 2023 Dec;
29:506-520.
PMID: 38160303
The microbes present in the human gastrointestinal tract are regularly linked to human health and disease outcomes. Thanks to technological and methodological advances in recent years, metagenomic sequencing data, and...
5.
Liu Y, Sapoval N, Gallego-Garcia P, Tomas L, Posada D, Treangen T, et al.
medRxiv
. 2023 Nov;
PMID: 37986916
We present Crykey, a computational tool for rapidly identifying cryptic mutations of SARS-CoV-2. Specifically, we identify co-occurring single nucleotide mutations on the same sequencing read, called linked-read mutations, that are...
6.
Sapoval N, Liu Y, Lou E, Hopkins L, Ensor K, Schneider R, et al.
Nat Commun
. 2023 May;
14(1):2834.
PMID: 37198181
As clinical testing declines, wastewater monitoring can provide crucial surveillance on the emergence of SARS-CoV-2 variant of concerns (VoCs) in communities. In this paper we present QuaID, a novel bioinformatics...
7.
Wang M, Lou E, Sapoval N, Kim E, Kalvapalle P, Kille B, et al.
bioRxiv
. 2023 Feb;
PMID: 36824759
Tiled amplicon sequencing has served as an essential tool for tracking the spread and evolution of pathogens. Over 2 million complete SARS-CoV-2 genomes are now publicly available, most sequenced and...
8.
Walker K, Kalra D, Lowdon R, Chen G, Molik D, Soto D, et al.
F1000Res
. 2022 Oct;
11:530.
PMID: 36262335
In October 2021, 59 scientists from 14 countries and 13 U.S. states collaborated virtually in the Third Annual Baylor College of Medicine & DNANexus Structural Variation hackathon. The goal of...
9.
Sapoval N, Liu Y, Lou E, Hopkins L, Ensor K, Schneider R, et al.
medRxiv
. 2022 Jul;
PMID: 35898338
As clinical testing declines, wastewater monitoring can provide crucial surveillance on the emergence of SARS-CoV-2 variants of concern (VoC) in communities. Multiple recent studies support that wastewater-based SARS-CoV-2 detection of...
10.
Balaji A, Sapoval N, Seto C, Elworth R, Fu Y, Nute M, et al.
Comput Struct Biotechnol J
. 2022 Jul;
20:3208-3222.
PMID: 35832621
Characterizing metagenomes via kmer-based, database-dependent taxonomic classification has yielded key insights into underlying microbiome dynamics. However, novel approaches are needed to track community dynamics and genomic flux within metagenomes, particularly...