Nicola Franchi
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Explore the profile of Nicola Franchi including associated specialties, affiliations and a list of published articles.
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28
Citations
168
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Recent Articles
1.
Sacchi S, Malagoli D, Franchi N
Cells
. 2025 Jan;
13(24.
PMID: 39768196
The knowledge of comparative and developmental immunobiology has grown over the years and has been strengthened by the contributions of multi-omics research. High-performance microscopy, flow cytometry, scRNA sequencing, and the...
2.
Ballarin L, Peronato A, Malagoli D, Macor P, Sacchi S, Sales G, et al.
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39596065
The complement system is a pivotal component of innate immunity, extensively studied in vertebrates but also present in invertebrates. This study explores the existence of a terminal complement pathway in...
3.
Bergamini G, Sacchi S, Ferri A, Franchi N, Montanari M, Ahmad M, et al.
Biology (Basel)
. 2023 Jul;
12(7).
PMID: 37508422
After amputation, granular hemocytes infiltrate the blastema of regenerating cephalic tentacles of the freshwater snail . Here, the circulating phagocytic hemocytes were chemically depleted by injecting the snails with clodronate...
4.
Malagoli D, Franchi N, Sacchi S
Antioxidants (Basel)
. 2023 Jun;
12(6).
PMID: 37371996
Reactive oxygen species (ROS) are volatile and short-lived molecules playing important roles in several physiological functions, including immunity and physiological adaptation to unsuitable environmental conditions. In an eco-immunological view, the...
5.
Franchi N, Ballarin L, Cima F
Mar Drugs
. 2023 Feb;
21(2).
PMID: 36827115
By mining the transcriptome of the colonial ascidian , we identified a transcript for a novel styelin-like antimicrobial peptide, which we named botryllin. The gene is constitutively transcribed by circulating...
6.
Smith L, Crow R, Franchi N, Schrankel C
Dev Comp Immunol
. 2022 Nov;
140:104584.
PMID: 36343741
The vertebrate complement cascade is an essential host protection system that functions at the intersection of adaptive and innate immunity. However, it was originally assumed that complement was present only...
7.
Peronato A, Franchi N, Loriano B
Fish Shellfish Immunol
. 2020 Sep;
106:967-974.
PMID: 32919053
Toll-like receptors (TLRs) represent a well-known family of conserved pattern recognition receptors the importance of which, in non-self recognition, was demonstrated in both vertebrates and invertebrates. Tunicates represent the vertebrate...
8.
Peronato A, Franchi N, Ballarin L
Biology (Basel)
. 2020 Sep;
9(9).
PMID: 32882947
As an evolutionary ancient component of the metazoan immune defense toolkit, the complement system can modulate cells and humoral responses of both innate and (in jawed vertebrates) adaptive immunity. All...
9.
Peronato A, Drago L, Rothbacher U, Macor P, Ballarin L, Franchi N
Dev Comp Immunol
. 2019 Nov;
103:103530.
PMID: 31669308
In the present work, we investigated, in the colonial ascidian Botryllus schlosseri, the role of complement C3 (BsC3) in phagocytosis. We studied the modulation of BsC3 transcription in the course...
10.
Franchi N, Ballarin L, Peronato A, Cima F, Grimaldi A, Girardello R, et al.
Dev Comp Immunol
. 2018 Sep;
90:108-120.
PMID: 30236880
Cytotoxic morula cells (MCs) and phagocytes are the circulating immunocytes of the colonial ascidian Botryllus schlosseri: Both these cells can synthesise amyloid fibrils, supporting the idea that physiological amyloidogenesis is...