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Nicola Farrar

Explore the profile of Nicola Farrar including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 11
Citations 76
Followers 0
Related Specialties
General Medicine
Pharmacology
Pulmonary Medicine
Top 10 Co-Authors
Leila Rooshenas
Nicola Mills
Daisy Elliott
Julia Wade
Jenny L Donovan
Marcus Jepson
Bridget Young
Carmel Conefrey
Eric Lim
Chris A Rogers
Published In
Trials
BMJ Open
Hum Mutat
PLoS One
Lancet Respir Med
Affiliations
Soon will be listed here.
Recent Articles
1.
The role of healthcare professionals' communication in trial participation decisions: a qualitative investigation of recruitment consultations and patient interviews across three RCTs
Farrar N, Elliott D, Jepson M, Young B, Donovan J, Conefrey C, et al.
Trials . 2024 Dec; 25(1):829. PMID: 39695876
Background: Although the challenges of recruiting to randomised controlled trials (RCTs) are well documented, few studies have focused on the impact that the communication between recruiters and patients has on...
2.
Addressing barriers and identifying facilitators to support informed consent and recruitment in the Cavernous malformations A Randomised Effectiveness (CARE) pilot phase trial: insights from the integrated QuinteT recruitment intervention (QRI)
Wade J, Farrar N, Realpe A, Donovan J, Forsyth L, Harkness K, et al.
EClinicalMedicine . 2024 May; 71:102557. PMID: 38813441
Background: It was anticipated that recruitment to the Cavernous malformations: A Randomised Effectiveness (CARE) pilot randomised trial would be challenging. The trial compared medical management and surgery (neurosurgical resection or...
3.
Strategies to address recruitment to a randomised trial of surgical and non-surgical treatment for cancer: results from a complex recruitment intervention within the Mesothelioma and Radical Surgery 2 (MARS 2) study
Mills N, Farrar N, Warnes B, Ashton K, Harris R, Rogers C, et al.
BMJ Open . 2024 May; 14(5):e079108. PMID: 38760029
Objectives: Recruiting to randomised trials is often challenging particularly when the intervention arms are markedly different. The Mesothelioma and Radical Surgery 2 randomised controlled trial (RCT) compared standard chemotherapy with...
4.
Extended pleurectomy decortication and chemotherapy versus chemotherapy alone for pleural mesothelioma (MARS 2): a phase 3 randomised controlled trial
Lim E, Waller D, Lau K, Steele J, Pope A, Ali C, et al.
Lancet Respir Med . 2024 May; 12(6):457-466. PMID: 38740044
Background: Extended pleurectomy decortication for complete macroscopic resection for pleural mesothelioma has never been evaluated in a randomised trial. The aim of this study was to compare outcomes after extended...
5.
Did the evidence-based intervention (EBI) programme reduce inappropriate procedures, lessen unwarranted variation or lead to spill-over effects in the National Health Service?
Glynn J, Jones T, Bell M, Blazeby J, Burton C, Conefrey C, et al.
PLoS One . 2023 Sep; 18(9):e0290996. PMID: 37656701
Background: Health systems are under pressure to maintain services within limited resources. The Evidence-Based Interventions (EBI) programme published a first list of guidelines in 2019, which aimed to reduce inappropriate...
6.
Duroplasty for injured cervical spinal cord with uncontrolled swelling: protocol of the DISCUS randomized controlled trial
Saadoun S, Grassner L, Belci M, Cook J, Knight R, Davies L, et al.
Trials . 2023 Aug; 24(1):497. PMID: 37550727
Background: Cervical traumatic spinal cord injury is a devastating condition. Current management (bony decompression) may be inadequate as after acute severe TSCI, the swollen spinal cord may become compressed against...
7.
Non-COVID-19 UK clinical trials and the COVID-19 pandemic: impact, challenges and possible solutions
Lorenc A, Rooshenas L, Conefrey C, Wade J, Farrar N, Mills N, et al.
Trials . 2023 Jun; 24(1):424. PMID: 37349850
Introduction: The COVID-19 pandemic impacted the operationalisation of non-COVID-19 clinical trials globally, particularly site and participant recruitment and trial success/stoppage. Trials which anticipate recruitment challenges may embed methods such as...
8.
Understanding the perspectives of recruiters is key to improving randomised controlled trial enrolment: a qualitative evidence synthesis
Farrar N, Elliott D, Houghton C, Jepson M, Mills N, Paramasivan S, et al.
Trials . 2022 Oct; 23(1):883. PMID: 36266700
Background: Recruiting patients to randomised controlled trials (RCTs) is often reported to be challenging, and the evidence base for effective interventions that could be used by staff (recruiters) undertaking recruitment...
9.
Recruiters' perspectives and experiences of trial recruitment processes: a qualitative evidence synthesis protocol
Farrar N, Elliott D, Jepson M, Houghton C, Young B, Donovan J, et al.
BMJ Open . 2021 Oct; 11(10):e045233. PMID: 34686547
Introduction: Recruitment to randomised trials (RCTs) is often challenging. Reviews of interventions to improve recruitment have highlighted a paucity of effective interventions aimed at recruiters and the need for further...
10.
Patient and public involvement (PPI) in UK surgical trials: a survey and focus groups with stakeholders to identify practices, views, and experiences
Crocker J, Pratt-Boyden K, Hislop J, Rees S, Locock L, Olszowski S, et al.
Trials . 2019 Feb; 20(1):119. PMID: 30744684
Background And Aims: Historically, patient and public involvement (PPI) in the design and conduct of surgical trials has been absent or minimal, but it is now routinely recommended and even...