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Nicklas H Staunstrup

Explore the profile of Nicklas H Staunstrup including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 155
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Recent Articles
1.
van den Oord E, Xie L, Zhao M, Campbell T, Turecki G, Kahler A, et al.
Mol Psychiatry . 2023 Apr; 28(5):2088-2094. PMID: 37106120
Schizophrenia is a disabling disorder involving genetic predisposition in combination with environmental influences that likely act via dynamic alterations of the epigenome and the transcriptome but its detailed pathophysiology is...
2.
Clausen A, Durand S, Petersen R, Staunstrup N, Qvist P
Genes (Basel) . 2022 Jun; 13(6). PMID: 35741801
Bipolar disorder is a debilitating psychiatric condition that is shaped in a concerted interplay between hereditary and triggering risk factors. Profound depression and mania define the disorder, but high clinical...
3.
Staunstrup N, Petersen C, Fuglsang T, Starnawska A, Chernomorchenko A, Qvist P, et al.
Cytometry A . 2021 Nov; 101(4):298-310. PMID: 34842347
Isolation of multiple cell populations from limited starting material and with minimal influence on cell homeostasis and viability are common requirements in both basic and clinical research. Fluorescence-activated cell sorting...
4.
Bukowski L, Chernomorchenko A, Starnawska A, Mors O, Staunstrup N, Borglum A, et al.
J Physiol Sci . 2020 May; 70(1):26. PMID: 32414324
Neuropsin is a brain-expressed extracellular matrix serine protease that governs synaptic plasticity through activity-induced proteolytic cleavage of synaptic proteins. Its substrates comprise several molecules central to structural synaptic plasticity, and...
5.
Bak S, Staunstrup N, Starnawska A, Daugaard T, Nyengaard J, Nyegaard M, et al.
Mol Neurobiol . 2016 Dec; 55(1):668-681. PMID: 27995571
We here characterize the usability of archival formalin-fixed paraffin-embedded (FFPE) brain tissue as a resource for genetic and DNA methylation analyses with potential relevance for brain-manifested diseases. We analyzed FFPE...
6.
Staunstrup N, Starnawska A, Nyegaard M, Christiansen L, Nielsen A, Borglum A, et al.
Clin Epigenetics . 2016 Jul; 8:81. PMID: 27462375
Background: In utero and early-life experienced environmental exposures are suggested to play an important role in many multifactorial diseases potentially mediated through lasting effects on the epigenome. As the epigenome...
7.
Starnawska A, Demontis D, McQuillin A, OBrien N, Staunstrup N, Mors O, et al.
Clin Epigenetics . 2016 May; 8:52. PMID: 27175219
Bipolar disorder (BD) and schizophrenia (SZ) are known to share common genetic and psychosocial risk factors. A recent epigenome-wide association study performed on blood samples from SZ patients found significant...
8.
Liu C, Xiao L, Li F, Zhang H, Li Q, Liu H, et al.
Transgenic Res . 2014 Dec; 24(3):433-46. PMID: 25448263
The angiotensin I converting enzyme 2 (ACE2) is a key factor in the maintenance of intestinal homeostasis. Dysregulation of homeostasis can lead to inflammation of the colon (colitis), which can...
9.
Cai Y, Bak R, Krogh L, Staunstrup N, Moldt B, Corydon T, et al.
Nucleic Acids Res . 2013 Nov; 42(4):e28. PMID: 24270790
DNA transposon-based vectors have emerged as gene vehicles with a wide biomedical and therapeutic potential. So far, genomic insertion of such vectors has relied on the co-delivery of genetic material...
10.
Staunstrup N, Mikkelsen J
Curr Gene Ther . 2011 Jul; 11(5):350-62. PMID: 21745178
Gene vehicles derived from lentiviruses have become highly esteemed tools for gene transfer and genomic insertion in a wealth of cell types both in vivo and ex vivo. However, accumulating...