Nick R G Shrine
Overview
Explore the profile of Nick R G Shrine including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
1182
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0
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Recent Articles
1.
Wain L, Sayers I, Artigas M, Portelli M, Zeggini E, Obeidat M, et al.
PLoS Genet
. 2014 May;
10(5):e1004314.
PMID: 24786987
Chronic obstructive pulmonary disease (COPD) is a leading cause of global morbidity and mortality and, whilst smoking remains the single most important risk factor, COPD risk is heritable. Of 26...
2.
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction
Wilk J, Shrine N, Loehr L, Zhao J, Manichaikul A, Lopez L, et al.
Am J Respir Crit Care Med
. 2012 Jul;
186(7):622-32.
PMID: 22837378
Rationale: Genome-wide association studies (GWAS) have identified loci influencing lung function, but fewer genes influencing chronic obstructive pulmonary disease (COPD) are known. Objectives: Perform meta-analyses of GWAS for airflow obstruction,...
3.
Ehret G, Munroe P, Rice K, Bochud M, Johnson A, Chasman D, et al.
Nature
. 2011 Sep;
478(7367):103-9.
PMID: 21909115
Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm Hg systolic blood pressure or ...