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Nichole Coleman

Explore the profile of Nichole Coleman including associated specialties, affiliations and a list of published articles. Areas
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Citations 76
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Recent Articles
1.
Ceberio N, Le P, Bailey J, Vernard S, Coleman N, Carrasco Y, et al.
PLoS One . 2024 Feb; 19(2):e0294307. PMID: 38412191
Objective: The unprecedented events of 2020 required a pivot in scientific training to better prepare the biomedical research workforce to address global pandemics, structural racism, and social inequities that devastate...
2.
Olivan-Viguera A, Valero M, Pinilla E, Amor S, Garcia-Villalon A, Coleman N, et al.
Basic Clin Pharmacol Toxicol . 2016 Jan; 119(2):184-92. PMID: 26821335
Opening of intermediate-conductance calcium-activated potassium channels (KC a 3.1) produces membrane hyperpolarization in the vascular endothelium. Here, we studied the ability of two new KC a 3.1-selective positive-gating modulators, SKA-111...
3.
Coleman N, Nguyen H, Cao Z, Brown B, Jenkins D, Zolkowska D, et al.
Neurotherapeutics . 2014 Sep; 12(1):234-49. PMID: 25256961
Inhibitors of voltage-gated sodium channels (Na(v)) have been used as anticonvulsants since the 1940s, while potassium channel activators have only been investigated more recently. We here describe the discovery of...
4.
Coleman N, Brown B, Olivan-Viguera A, Singh V, Olmstead M, Valero M, et al.
Mol Pharmacol . 2014 Jun; 86(3):342-57. PMID: 24958817
Small-conductance (KCa2) and intermediate-conductance (KCa3.1) calcium-activated K(+) channels are voltage-independent and share a common calcium/calmodulin-mediated gating mechanism. Existing positive gating modulators like EBIO, NS309, or SKA-31 activate both KCa2 and...
5.
Lam J, Coleman N, Garing A, Wulff H
Expert Opin Ther Targets . 2013 Jul; 17(10):1203-20. PMID: 23883298
Introduction: KCa2 or small-conductance Ca(2+)-activated K(+) channels (SK) are expressed in many areas of the central nervous system where they participate in the regulation of neuronal afterhyperpolarization and excitability, and...
6.
Bodendiek S, Rubinos C, Trelles M, Coleman N, Jenkins D, Wulff H, et al.
Front Pharmacol . 2012 Jun; 3:106. PMID: 22685432
The paucity of specific pharmacological agents has been a major impediment for delineating the roles of gap junction (GJ) channels formed by connexin proteins in physiology and pathophysiology. Here, we...