Nicholas R Anthonisen
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Explore the profile of Nicholas R Anthonisen including associated specialties, affiliations and a list of published articles.
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30
Citations
1761
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Recent Articles
1.
Anthonisen N
J Appl Physiol (1985)
. 2019 May;
18(3):539-543.
PMID: 31095344
The pulmonary mechanics of anesthetized rabbits were studied during induced acute bronchoconstriction. The bronchoconstricting agent was acetyl-β-methylcholine which, when injected intravenously as in these experiments, appeared to act via the...
2.
Wang Y, Shumansky K, Sin D, Paul Man S, Akhabir L, Connett J, et al.
Int J Clin Exp Pathol
. 2016 Jan;
8(10):13125-35.
PMID: 26722511
Objective: We reported association of haplotypes formed by IL-1b (IL1B)-511C/T (rs16944) and a variable number of tandem repeats (rs2234663) in intron 3 of IL-1 receptor antagonist (IL1RN) with rate of...
3.
Sandford A, Malhotra D, Boezen H, Siedlinski M, Postma D, Wong V, et al.
Physiol Genomics
. 2012 Jun;
44(15):754-63.
PMID: 22693272
An oxidant-antioxidant imbalance in the lung contributes to the development of chronic obstructive pulmonary disease (COPD) that is caused by a complex interaction of genetic and environmental risk factors. Nuclear...
4.
Lee J, Sandford A, Connett J, Yan J, Mui T, Li Y, et al.
PLoS One
. 2012 May;
7(4):e35567.
PMID: 22558169
Some have suggested that chronic obstructive pulmonary disease (COPD) is a disease of accelerated aging. Aging is characterized by shortening of telomeres. The relationship of telomere length to important clinical...
5.
Casaburi R, Porszasz J, Hecht A, Tiep B, Albert R, Anthonisen N, et al.
COPD
. 2012 Feb;
9(1):3-11.
PMID: 22292592
Lightweight ambulatory oxygen devices are provided on the assumptions that they enhance compliance and increase activity, but data to support these assumptions are lacking. We studied 22 patients with severe...
6.
Tanaka G, Aminuddin F, Akhabir L, He J, Shumansky K, Connett J, et al.
BMC Med Genet
. 2011 Sep;
12:117.
PMID: 21902835
Background: Oxidative stress induced by smoking is considered to be important in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD). Heme oxygenase-1 (HMOX1) is an essential enzyme in heme catabolism...
7.
Albert R, Connett J, Bailey W, Casaburi R, Cooper Jr J, Criner G, et al.
N Engl J Med
. 2011 Aug;
365(8):689-98.
PMID: 21864166
Background: Acute exacerbations adversely affect patients with chronic obstructive pulmonary disease (COPD). Macrolide antibiotics benefit patients with a variety of inflammatory airway diseases. Methods: We performed a randomized trial to...
8.
Hackett T, Stefanowicz D, Aminuddin F, Sin D, Connett J, Anthonisen N, et al.
Int J Chron Obstruct Pulmon Dis
. 2011 Aug;
6:277-87.
PMID: 21814463
Background: The objective of this study was to determine if gene-environment interactions between cigarette smoking and interleukin-6 (IL6), interferon-γ (IFNG), interleukin-1β (IL1B), or interleukin-1 receptor antagonist (IL1RN) single nucleotide polymorphisms...
9.
Dransfield M, Nahm M, Han M, Harnden S, Criner G, Martinez F, et al.
Am J Respir Crit Care Med
. 2009 Jun;
180(6):499-505.
PMID: 19556517
Rationale: Debate exists about the immunogenicity and protective efficacy of antibodies produced by the 23-valent pneumococcal polysaccharide vaccine (PPSV23) in chronic obstructive pulmonary disease (COPD). The 7-valent diphtheria-conjugated pneumococcal polysaccharide...
10.
Mastronarde J, Anthonisen N, Castro M, Holbrook J, Leone F, Teague W, et al.
N Engl J Med
. 2009 Apr;
360(15):1487-99.
PMID: 19357404
Background: Gastroesophageal reflux is common among patients with asthma but often causes mild or no symptoms. It is not known whether treatment of gastroesophageal reflux with proton-pump inhibitors in patients...