Nicholas Peake
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Explore the profile of Nicholas Peake including associated specialties, affiliations and a list of published articles.
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7
Citations
44
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Recent Articles
1.
Al-Bari M, Peake N, Eid N
World J Diabetes
. 2024 May;
15(5):853-866.
PMID: 38766427
Tuberculosis (TB) remains a leading cause of death among infectious diseases, particularly in poor countries. Viral infections, multidrug-resistant and ex-tensively drug-resistant TB strains, as well as the coexistence of chronic...
2.
Betsuyaku T, Ito Y, Peake N, Al-Bari A, El-Akabawy G, Eid N
Histol Histopathol
. 2024 Mar;
39(7):853-866.
PMID: 38465764
Autophagy is a prosurvival mechanism for the clearance of damaged cellular components, specifically upon exposure to various stressors. In lymphoid organs, excessive ethanol consumption increases lymphocyte apoptosis, resulting in immunosuppression....
3.
Guarnerio S, Tempest R, Maani R, Hunt S, Cole L, Le Maitre C, et al.
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38069076
The development of novel screening tests aims to support early asymptomatic diagnosis and subtyping patients according to similar traits in the heterogeneous cancer cohort. Extracellular vesicles (EVs) are promising candidates...
4.
Al-Bari A, Ito Y, Thomes P, Menon M, Garcia-Macia M, Fadel R, et al.
Front Pharmacol
. 2023 Apr;
14:1149809.
PMID: 37007026
Macroautophagy (hereafter referred to as autophagy), a highly conserved metabolic process, regulates cellular homeostasis by degrading dysfunctional cytosolic constituents and invading pathogens the lysosomal system. In addition, autophagy selectively recycles...
5.
Tempest R, Guarnerio S, Maani R, Cooper J, Peake N
Cancers (Basel)
. 2021 Jul;
13(11).
PMID: 34205140
Transglutaminase-2 (TG2) is the most highly and ubiquitously expressed member of the transglutaminase enzyme family and is primarily involved in protein cross-linking. TG2 has been implicated in the development and...
6.
Delaine-Smith R, Wright N, Hanley C, Hanwell R, Bhome R, Bullock M, et al.
Cancers (Basel)
. 2019 May;
11(5).
PMID: 31117256
Colorectal cancer is the third most common cancer worldwide, and the fourth leading cause of malignancy-related mortality. This highlights the need to understand the processes driving this disease in order...
7.
Natriuretic peptide receptors regulate cytoprotective effects in a human ex vivo 3D/bioreactor model
Peake N, Su N, Ramachandran M, Achan P, Salter D, Bader D, et al.
Arthritis Res Ther
. 2013 Jul;
15(4):R76.
PMID: 23883591
Introduction: The present study examined the effect of C-type natriuretic peptide (CNP) and biomechanical signals on anabolic and catabolic activities in chondrocyte/agarose constructs. Methods: Natriuretic peptide (Npr) 2 and 3...