Nicholas Joza
Overview
Explore the profile of Nicholas Joza including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
1621
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0
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Recent Articles
1.
Joza N, Saif M
JOP
. 2014 Jul;
15(4):308-9.
PMID: 25076328
Pancreatic adenocarcinoma is a highly aggressive cancer, with a median patient survival of less than one year. Clinically useful biomarkers capable of accurately assessing prognosis, as well as response to...
2.
Vitale I, Senovilla L, Jemaa M, Michaud M, Galluzzi L, Kepp O, et al.
EMBO J
. 2010 Feb;
29(7):1272-84.
PMID: 20186124
Tetraploidy can constitute a metastable intermediate between normal diploidy and oncogenic aneuploidy. Here, we show that the absence of p53 is not only permissive for the survival but also for...
3.
McQuibban A, Joza N, Megighian A, Scorzeto M, Zanini D, Reipert S, et al.
Hum Mol Genet
. 2009 Dec;
19(6):987-1000.
PMID: 20026556
Human Wolf-Hirschhorn syndrome (WHS) is a multigenic disorder resulting from a hemizygous deletion on chromosome 4. LETM1 is the best candidate gene for seizures, the strongest haploinsufficiency phenotype of WHS...
4.
Joza N, Pospisilik J, Hangen E, Hanada T, Modjtahedi N, Penninger J, et al.
Ann N Y Acad Sci
. 2009 Sep;
1171:2-11.
PMID: 19723031
Since its discovery nearly a decade ago, apoptosis-inducing factor (AIF) has had anything but a staid and uneventful existence. AIF was originally described as a mitochondrial intermembrane protein that, after...
5.
Senovilla L, Vitale I, Galluzzi L, Vivet S, Joza N, Younes A, et al.
Cell Cycle
. 2009 Apr;
8(9):1380-5.
PMID: 19342895
Tetraploidy may constitute a metastable state leading to numeric and structural chromosome abnormalities that are associated with cancer. Here, we show that cultured primary p53(-/-) (but not wild type, WT)...
6.
Panaretakis T, Kepp O, Brockmeier U, Tesniere A, Bjorklund A, Chapman D, et al.
EMBO J
. 2009 Jan;
28(5):578-90.
PMID: 19165151
Dying tumour cells can elicit a potent anticancer immune response by exposing the calreticulin (CRT)/ERp57 complex on the cell surface before the cells manifest any signs of apoptosis. Here, we...
7.
Galluzzi L, Morselli E, Vicencio J, Kepp O, Joza N, Tajeddine N, et al.
Biochem Soc Trans
. 2008 Sep;
36(Pt 5):786-90.
PMID: 18793137
Macroautophagy, often referred to as autophagy, designates the process by which portions of the cytoplasm, intracellular organelles and long-lived proteins are engulfed in double-membraned vacuoles (autophagosomes) and sent for lysosomal...
8.
Tesniere A, Apetoh L, Ghiringhelli F, Joza N, Panaretakis T, Kepp O, et al.
Curr Opin Immunol
. 2008 Jun;
20(5):504-11.
PMID: 18573340
Physiological cell death, which occurs as a continuous byproduct of cellular turnover, is non-immunogenic or even tolerogenic, thereby avoiding autoimmunity. By contrast, cancer cell death elicited by radiotherapy and some...
9.
Pospisilik J, Knauf C, Joza N, Benit P, Orthofer M, Cani P, et al.
Cell
. 2007 Nov;
131(3):476-91.
PMID: 17981116
Type-2 diabetes results from the development of insulin resistance and a concomitant impairment of insulin secretion. Recent studies place altered mitochondrial oxidative phosphorylation (OxPhos) as an underlying genetic element of...
10.
Cheung E, Joza N, Steenaart N, McClellan K, Neuspiel M, McNamara S, et al.
EMBO J
. 2006 Aug;
25(17):4061-73.
PMID: 16917506
The mitochondrial protein apoptosis-inducing factor (AIF) translocates to the nucleus and induces apoptosis. Recent studies, however, have indicated the importance of AIF for survival in mitochondria. In the absence of...