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Nicholas J Wong

Explore the profile of Nicholas J Wong including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 141
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Recent Articles
1.
Jaimes E, Zhou M, Siddiqui M, Rezonzew G, Tian R, Seshan S, et al.
Am J Physiol Renal Physiol . 2021 Jan; 320(3):F442-F453. PMID: 33459165
Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease. Besides glycemic and blood pressure control, environmental factors such as cigarette smoking (CS) adversely affect the progression of DN....
2.
Egerman M, Wong J, Runxia T, Mosoyan G, Chauhan K, Reyes-Bahamonde J, et al.
FASEB J . 2020 Oct; 34(12):16191-16204. PMID: 33070369
Urinary plasminogen/plasmin, or plasmin (ogen) uria, has been demonstrated in proteinuric patients and exposure of cultured podocytes to plasminogen results in injury via oxidative stress pathways. A causative role for...
3.
Ge X, Zhang T, Yu X, Muwonge A, Anandakrishnan N, Wong N, et al.
J Am Soc Nephrol . 2020 Aug; 31(10):2372-2391. PMID: 32737144
Background: Maintenance of the intricate interdigitating morphology of podocytes is crucial for glomerular filtration. One of the key aspects of specialized podocyte morphology is the segregation and organization of distinct...
4.
Zhong Y, Lee K, Deng Y, Ma Y, Chen Y, Li X, et al.
Nat Commun . 2019 Oct; 10(1):4523. PMID: 31586053
Arctigenin (ATG) is a major component of Fructus Arctii, a traditional herbal remedy that reduced proteinuria in diabetic patients. However, whether ATG specifically provides renoprotection in DKD is not known....
5.
Calizo R, Bhattacharya S, van Hasselt J, Wei C, Wong J, Wiener R, et al.
Nat Commun . 2019 May; 10(1):2061. PMID: 31053734
Nephrotoxicity is a critical adverse event that leads to discontinuation of kinase inhibitor (KI) treatment. Here we show, through meta-analyses of FDA Adverse Event Reporting System, that dasatinib is associated...