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Nicholas J Norton

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Recent Articles
1.
Brendish N, Tanner A, Poole S, Beard K, Naidu V, Mansbridge C, et al.
Infect Dis Ther . 2022 May; 11(3):1267-1280. PMID: 35534764
Introduction: RT-PCR has suboptimal sensitivity for the diagnosis of COVID-19. A composite reference standard comprising RT-PCR plus radiological and clinical features has been recommended for diagnostic accuracy studies. The FebriDx...
2.
Mansbridge C, Norton N, Fox S
Am J Trop Med Hyg . 2020 Nov; 104(2):731-733. PMID: 33236700
Eosinophilic meningitis is classically caused by Angiostrongylus cantonensis. Treatment usually includes supportive care and corticosteroids. Anthelminthic drugs are often avoided because of the risk of an inflammatory reaction to dying...
3.
Brendish N, Poole S, Naidu V, Mansbridge C, Norton N, Wheeler H, et al.
Lancet Respir Med . 2020 Oct; 8(12):1192-1200. PMID: 33038974
Background: The management of the COVID-19 pandemic is hampered by long delays associated with centralised laboratory PCR testing. In hospitals, these delays lead to poor patient flow and nosocomial transmission....
4.
Norton N, Mok H, Sharif F, Hirst J, Lever A
mBio . 2019 Jun; 10(3). PMID: 31239371
Transcriptionally silent HIV proviruses form the major obstacle to eradicating HIV. Many studies of HIV latency have focused on the cellular mechanisms that maintain silencing of proviral DNA. Here we...
5.
Mok H, Norton N, Hirst J, Fun A, Bandara M, Wills M, et al.
Sci Rep . 2018 Feb; 8(1):2639. PMID: 29422601
The persistence of infected T cells harbouring intact HIV proviruses is the barrier to the eradication of HIV. This reservoir is stable over long periods of time despite antiretroviral therapy....
6.
Norton N, Fun A, Bandara M, Wills M, Mok H, Lever A
Retrovirology . 2017 Dec; 14(1):58. PMID: 29268753
A robust measure of the size of the latent HIV reservoir is essential to quantifying the effect of interventions designed to deplete the pool of reactivatable, replication competent proviruses. In...