Nicholas Dopkins
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Explore the profile of Nicholas Dopkins including associated specialties, affiliations and a list of published articles.
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21
Citations
231
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Recent Articles
11.
Dopkins N, Singh B, Michael S, Omara M, Marston J, Fei T, et al.
mBio
. 2023 Jan;
14(1):e0328022.
PMID: 36645307
Transposable elements (TEs) are mobile genomic sequences that encompass roughly 50% of the human genome. Class 1 TEs, or "retrotransposons," mobilize through the production of an RNA intermediate that is...
12.
Dopkins N, Omara M, Lawrence E, Fei T, Sandoval-Motta S, Nixon D, et al.
Mol Cell
. 2022 Oct;
82(20):3763-3768.
PMID: 36270247
Germ cells are subject to exogenous retrovirus infections occasionally resulting in the genomic integration of retroviral gene sequences. These endogenized retroviruses (ERVs) are found throughout mammalian genomes. Initially thought to...
13.
Dopkins N, Nixon D
Trends Microbiol
. 2022 Sep;
31(5):430-431.
PMID: 36153261
Retroviral DNA induces the production of interferons. A new study by Yoh et al. showed that the host factor 'PQBP1' primes immune-recognition of retroviral DNA by recruiting the cytosolic DNA...
14.
Miranda K, Becker W, Busbee P, Dopkins N, Abdulla O, Zhong Y, et al.
iScience
. 2022 Sep;
25(9):104994.
PMID: 36093055
While blockade of cannabinoid receptor 1 (CB1) has been shown to attenuate diet-induced obesity (DIO), its relative role in different cell types has not been tested. The current study investigated...
15.
Cannon A, Holloman B, Wilson K, Miranda K, Dopkins N, Nagarkatti P, et al.
Front Immunol
. 2022 Jun;
13:899609.
PMID: 35720411
The aryl hydrocarbon receptor (AhR) is a ubiquitously expressed ligand-activated transcription factor. While initially identified as an environmental sensor, this receptor has been shown more recently to regulate a variety...
16.
Dopkins N, Omara M, Singh B, Marston J, Bendall M, Nixon D
Trends Microbiol
. 2022 Jun;
30(9):812-815.
PMID: 35672223
The microbiota is a collective of microorganisms whose composition is intimately linked with human health and disease. Emerging evidence demonstrates that endogenous retroviruses facilitate crosstalk between the host and microbiota...
17.
Dopkins N, Neameh W, Hall A, Lai Y, Rutkovsky A, Gandy A, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769237
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a polyhalogenated planar hydrocarbon belonging to a group of highly toxic and persistent environmental contaminants known as "dioxins". TCDD is an animal teratogen and carcinogen that is...
18.
Dopkins N, Miranda K, Wilson K, Holloman B, Nagarkatti P, Nagarkatti M
J Neuroimmune Pharmacol
. 2021 Nov;
17(1-2):15-32.
PMID: 34757526
Cannabidiol (CBD) is a bioactive compound isolated from Cannabis plants that has garnered attention within the medical community due to its potent anti-inflammatory properties. To better understand how CBD limits...
19.
Dopkins N, Becker W, Miranda K, Walla M, Nagarkatti P, Nagarkatti M
Front Pharmacol
. 2021 Feb;
11:619265.
PMID: 33569008
Tryptamine is a naturally occurring monoamine alkaloid which has been shown to act as an aryl hydrocarbon receptor (AHR) agonist. It is produced in large quantities from the catabolism of...
20.
Busbee P, Menzel L, Alrafas H, Dopkins N, Becker W, Miranda K, et al.
JCI Insight
. 2020 Jan;
5(1).
PMID: 31941837
Colitis, an inflammatory bowel disease, is caused by a variety of factors, but luminal microbiota are thought to play crucial roles in disease development and progression. Indole is produced by...