Nicholas D Evans
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Explore the profile of Nicholas D Evans including associated specialties, affiliations and a list of published articles.
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42
Citations
1501
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Recent Articles
21.
Moreno-Jimenez I, Lanham S, Kanczler J, Hulsart-Billstrom G, Evans N, Oreffo R
J Tissue Eng Regen Med
. 2018 Jun;
12(8):1877-1890.
PMID: 29893478
Traditionally used as an angiogenic assay, the chorioallantoic membrane (CAM) assay of the chick embryo offers significant potential as an in vivo model for xenograft organ culture. Viable human bone...
22.
Tusan C, Man Y, Zarkoob H, Johnston D, Andriotis O, Thurner P, et al.
Biophys J
. 2018 Jun;
114(11):2743-2755.
PMID: 29874622
Extracellular matrix stiffness has a profound effect on the behavior of many cell types. Adherent cells apply contractile forces to the material on which they adhere and sense the resistance...
23.
Scarpa E, Janeczek A, Hailes A, de Andres M, De Grazia A, Oreffo R, et al.
Nanomedicine
. 2018 Mar;
14(4):1267-1277.
PMID: 29555223
Spatiotemporal control of drug delivery is important for a number of medical applications and may be achieved using polymersome nanoparticles (PMs). Wnt signalling is a molecular pathway activated in various...
24.
Mousa M, Evans N, Oreffo R, Dawson J
Biomaterials
. 2018 Jan;
159:204-214.
PMID: 29331807
Clay nanoparticles, composites and hydrogels are emerging as a new class of biomaterial with exciting potential for tissue engineering and regenerative medicine applications. Clay particles have been extensively explored in...
25.
Lippert A, Janeczek A, Furstenberg A, Ponjavic A, Moerner W, Nusse R, et al.
Biophys J
. 2017 Dec;
113(12):2762-2767.
PMID: 29262368
Wnt proteins are secreted, hydrophobic, lipidated proteins found in all animals that play essential roles in development and disease. Lipid modification is thought to facilitate the interaction of the protein...
26.
Janeczek A, Scarpa E, Horrocks M, Tare R, Rowland C, Jenner D, et al.
Nanomedicine (Lond)
. 2017 Mar;
12(8):845-863.
PMID: 28351228
Aim: To fabricate PEGylated liposomes which preserve the activity of hydrophobic Wnt3A protein, and to demonstrate their efficacy in promoting expansion of osteoprogenitors from human bone marrow. Methods: PEGylated liposomes...
27.
Moreno-Jimenez I, Hulsart-Billstrom G, Lanham S, Janeczek A, Kontouli N, Kanczler J, et al.
Sci Rep
. 2016 Sep;
6:32168.
PMID: 27577960
Biomaterial development for tissue engineering applications is rapidly increasing but necessitates efficacy and safety testing prior to clinical application. Current in vitro and in vivo models hold a number of...
28.
Scarpa E, Bailey J, Janeczek A, Stumpf P, Johnston A, Oreffo R, et al.
Sci Rep
. 2016 Jul;
6:29460.
PMID: 27404770
Polymersome nanoparticles (PMs) are attractive candidates for spatio-temporal controlled delivery of therapeutic agents. Although many studies have addressed cellular uptake of solid nanoparticles, there is very little data available on...
29.
Nitiputri K, Ramasse Q, Autefage H, McGilvery C, Boonrungsiman S, Evans N, et al.
ACS Nano
. 2016 Jul;
10(7):6826-35.
PMID: 27383526
A direct observation and an in-depth characterization of the steps by which bone mineral nucleates and grows in the extracellular matrix during the earliest stages of maturation, using relevant biomineralization...
30.
Janeczek A, Tare R, Scarpa E, Moreno-Jimenez I, Rowland C, Jenner D, et al.
Stem Cells
. 2015 Nov;
34(2):418-30.
PMID: 26573091
Activation of the canonical Wnt signaling pathway is an attractive anabolic therapeutic strategy for bone. Emerging data suggest that activation of the Wnt signaling pathway promotes bone mineral accrual in...