Nicholas D Carter
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Explore the profile of Nicholas D Carter including associated specialties, affiliations and a list of published articles.
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21
Citations
376
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Recent Articles
1.
Gillies R, Robinson S, McPhail L, Carter N, Murray J
J Mol Histol
. 2011 Jul;
42(4):341-54.
PMID: 21732047
Hypoxia is thought to be critical in regulating physiological processes within the female reproductive system, including ovulation, composition of the fluid in the oviductal/uterine lumens and ovarian follicle development. This...
2.
Nolte I, Wallace C, Newhouse S, Waggott D, Fu J, Soranzo N, et al.
PLoS One
. 2009 Jul;
4(7):e6138.
PMID: 19587794
To identify loci affecting the electrocardiographic QT interval, a measure of cardiac repolarisation associated with risk of ventricular arrhythmias and sudden cardiac death, we conducted a meta-analysis of three genome-wide...
3.
Pipinikas C, Carter N, Corbishley C, Fenske C
Biomarkers
. 2008 Dec;
13(7):680-91.
PMID: 19096962
Objectives: Several clinical studies have indicated that the rates of invasive growth and metastatic disease in cancer depend on the degree of hypoxia, which is mediated by hypoxia-inducible factor 1...
4.
Dalageorgou C, Ge D, Jamshidi Y, Nolte I, Riese H, Savelieva I, et al.
J Cardiovasc Electrophysiol
. 2007 Nov;
19(4):386-91.
PMID: 18031506
Introduction: Objective of this study was to determine the optimal (most heritable) phenotype for gene finding studies of QT interval in the general population. We also studied the extent to...
5.
Pipinikas C, Nair S, Kirby R, Carter N, Fenske C
Biomarkers
. 2007 Aug;
12(5):541-57.
PMID: 17701752
The use of serum prostate-specific antigen (PSA) measurements necessitates biopsies for accurate prostate cancer (CaP) diagnosis. Overall efficiency of accurate diagnosis, when PSA levels are used alone, is less than...
6.
Fredericks S, Jorga A, MacPhee I, Reboux S, Shiferaw E, Moreton M, et al.
Clin Transplant
. 2007 Apr;
21(2):252-7.
PMID: 17425754
The intestinal efflux pump P-glycoprotein (P-gp), the product of the multi-drug resistance-1 (MDR-1) gene, significantly influences the pharmacokinetics of several drugs. Ciclosporin is a substrate for P-gp and is metabolized...
7.
Fredericks S, Moreton M, Reboux S, Carter N, Goldberg L, Holt D, et al.
Transplantation
. 2006 Sep;
82(5):705-8.
PMID: 16969296
P-glycoprotein (P-gp) and the drug metabolizing enzymes have major pharmacokinetic effects. Variability in tacrolimus absorption is influenced by P-gp activity which, in turn, is affected by single nucleotide polymorphisms (SNPs)...
8.
Spencer-Jones N, Wang X, Snieder H, Spector T, Carter N, ODell S
Diabetes
. 2005 Oct;
54(11):3296-304.
PMID: 16249458
Protein tyrosine phosphatase-1B negatively regulates leptin and insulin signaling, potentially contributing to hormonal resistance. We selected six tagging single nucleotide polymorphisms (SNPs) representing 18 common variants in the protein tyrosine...
9.
Fredericks S, Moreton M, MacPhee I, Mohamed M, Marlowe S, Jorga A, et al.
Ann Clin Biochem
. 2005 Sep;
42(Pt 5):376-81.
PMID: 16168193
Cytochrome P450 3A5 (CYP3A5) is involved in the biotransformation of many orally administered drugs, some of which are dose optimized using therapeutic drug monitoring. The CYP3A5 gene exhibits variable inter-individual...
10.
Chen Y, Snieder H, Wang X, Kaviya B, McCaffrey C, Spector T, et al.
Eur J Hum Genet
. 2005 Apr;
13(6):772-80.
PMID: 15812563
A major quantitative trait locus (QTL) determining leptin levels has been linked to the proopiomelanocortin (POMC) region on chromosome 2. Most studies, based on under 350 lean or obese subjects,...