Nicholas Chester
Overview
Explore the profile of Nicholas Chester including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
5
Citations
94
Followers
0
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Recent Articles
1.
Yoshimoto S, Chester N, Xiong A, Radaelli E, Wang H, Brillantes M, et al.
MAbs
. 2023 Dec;
15(1):2287250.
PMID: 38047502
PD-1 checkpoint inhibitors have revolutionized the treatment of patients with different cancer histologies including melanoma, renal cell carcinoma, and non-small cell lung carcinoma. However, only a subset of patients show...
2.
Mason N, Chester N, Xiong A, Rotolo A, Wu Y, Yoshimoto S, et al.
MAbs
. 2021 Dec;
13(1):2004638.
PMID: 34856888
The immune checkpoint inhibitor (ICI) ipilimumab has revolutionized the treatment of patients with different cancer histologies, including melanoma, renal cell carcinoma, and non-small cell lung carcinoma. However, only a subset...
3.
Babbe H, Chester N, Leder P, Reizis B
Mol Cell Biol
. 2007 Jan;
27(5):1947-59.
PMID: 17210642
Bloom's syndrome is a genetic disorder characterized by increased incidence of cancer and an immunodeficiency of unknown origin. The BLM gene mutated in Bloom's syndrome encodes a DNA helicase involved...
4.
Chester N, Babbe H, Pinkas J, Manning C, Leder P
Mol Cell Biol
. 2006 Aug;
26(17):6713-26.
PMID: 16914751
Bloom's syndrome (BS) is a genetic disorder characterized cellularly by increases in sister chromatid exchanges (SCEs) and numbers of micronuclei. BS is caused by mutation in the BLM DNA helicase...
5.
McDaniel L, Chester N, Watson M, Borowsky A, Leder P, Schultz R
DNA Repair (Amst)
. 2003 Dec;
2(12):1387-404.
PMID: 14642567
Independent mouse models for Bloom syndrome (BS) exist, each thought to disrupt Blm gene function. However, animals bearing these alleles exhibit distinct phenotypes. Blm(tm1Ches) and Blm(tm1Grdn) homozygous mutant animals exhibit...